Objectives: Significantly low serum levels of complement components have been reported in
patients with Sickle cell anaemia (SCA) which may result in a high susceptibility to …

Sickle cell disease is an hereditary hemoglobinopathy syndrome which provokes
deglobulization crisis and infectious complications. These infectious diseases may be due to …

Background: Sickle cell anaemia (SCA) is a hereditary disorder associated with high
morbidity and mortality. The objective of this study is to determine the haematological …

Background: Impaired immunological function such as a reduction in the T cell component
has been reported in patients with Sickle cell anaemia (SCA), leading to loss of both …

Background: Sickle cell anemia (SCA) is an inherited hemoglobin disorder characterized by
chronic anemia and occasional crises. Clinical features are variable. While some individuals …

Background: Sickle cell disease (SCD) remains a major health burden in Sub-Saharan
Africa and the management requires regular monitoring of the patients. The monitoring …

Aim: The aim of this study is to investigate some immuno-haematological characteristics of
Nigerian sickle cell disease (SCD) patients in asymptomatic steady state. Material and …

Methods This cross-sectional study was conducted at the University of Maiduguri Teaching
Hospital, North-Eastern Nigeria, from October 2020 to May 2021. All febrile and/or acutely ill …

Background: Sickle cell disease (SCD) is an inherited chronic haemolytic disorder that is
characterised by chronic anaemia and recurrent body pains, with Nigeria accounting for the …

Background: There are documented established markers (indices) of disease severity in
patients with sickle cell anemia (SCA) and they determine the course of the disease. This …