Role of berberine in Alzheimer's disease

Z Cai, C Wang, W Yang - Neuropsychiatric disease and treatment, 2016 - Taylor & Francis
Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Neuroprotective potential of berberine in modulating Alzheimer's disease via multiple signaling pathways

M Akbar, A Shabbir, K Rehman… - Journal of food …, 2021 - Wiley Online Library
Berberine is one of the most important quinoline alkaloids, which has shown numerous
pharmacological activities. There are pieces of evidence that berberine serves as a …

Berberine: a plant-derived alkaloid with therapeutic potential to combat Alzheimer's disease

AK Singh, SK Singh, MK Nandi… - … System Agents in …, 2019 - ingentaconnect.com
Berberine (a protoberberine isoquinoline alkaloid) has shown promising pharmacological
activities, including analgesic, anti-inflammatory, anticancer, antidiabetic, anti …

Berberine: a promising treatment for neurodegenerative diseases

Z Cheng, C Kang, S Che, J Su, Q Sun, T Ge… - Frontiers in …, 2022 - frontiersin.org
Berberine, as a natural alkaloid compound, is characterized by a diversity of
pharmacological effects. In recent years, many researches focused on the role of berberine …

Berberine: a potential multipotent natural product to combat Alzheimer's disease

HF Ji, L Shen - Molecules, 2011 - mdpi.com
With the accelerated aging of human society Alzheimer's disease (AD) has become one of
the most threatening diseases in the elderly. However, there is no efficient therapeutic agent …

Therapeutic potential of berberine against neurodegenerative diseases

WX Jiang, SH Li, XJ Li - Science China Life Sciences, 2015 - Springer
Berberine (BBR) is an organic small molecule isolated from various plants that have been
used in traditional Chinese medicine. Isolation of this compound was its induction into …

Berberine and neurodegeneration: A review of literature

T Ahmed, M Abdollahi, M Daglia, SF Nabavi… - Pharmacological …, 2015 - Elsevier
The excessive production of reactive oxygen species in nervous tissues is considered one of
the major risk factors of neurodegenerative diseases. During the last two decades, much …

Neuroprotective effects of berberine in animal models of Alzheimer's disease: a systematic review of pre-clinical studies

NN Yuan, CZ Cai, MY Wu, HX Su, M Li… - BMC complementary and …, 2019 - Springer
Background Berberine is an isoquinoline alkaloid extracted from various Berberis species
which is widely used in East Asia for a wide range of symptoms. Recently, neuroprotective …

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review

N Shinjyo, J Parkinson, J Bell, T Katsuno… - Journal of integrative …, 2020 - Elsevier
Background A growing number of epidemiological studies indicate that metabolic syndrome
(MetS) and its associated features play a key role in the development of certain …

Berberine alters the processing of Alzheimer's amyloid precursor protein to decrease Aβ secretion

M Asai, N Iwata, A Yoshikawa, Y Aizaki… - Biochemical and …, 2007 - Elsevier
Berberine is an isoquinoline alkaloid isolated from Coptidis rhizoma, a major herb widely
used in Chinese herbal medicine. Berberine's biological activity includes antidiarrheal …