K+ Channel-Dependent Migration of Fibroblasts and Human Melanoma Cells

A Schwab, J Reinhardt, SW Schneider… - Cellular Physiology and …, 1999 - karger.com
Previously, we showed that migration of transformed renal epithelial cells (MDCK-F cells) is
a K+ channel-dependent process [J Clin Invest 1994; 93: 1631]. In order to determine …

Oscillating activity of a Ca (2+)-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells.

A Schwab, L Wojnowski, K Gabriel… - The Journal of …, 1994 - Am Soc Clin Investig
Migration plays an important role in the formation of tumor metastases. Nonetheless, little is
known about electrophysiological phenomena accompanying or underlying migration …

Polarized ion transport during migration of transformed Madin-Darby canine kidney cells

A Schwab, K Gabriel, F Finsterwalder, G Folprecht… - Pflügers Archiv, 1995 - Springer
Epithelial cells lose their usual polarization during carcinogenesis. Although most malignant
tumours are of epithelial origin little is known about ion channels in carcinoma cells …

Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume

A Schwab, B Schuricht, P Seeger, J Reinhardt… - Pflügers Archiv, 1999 - Springer
Migration of transformed renal epithelial (MDCK-F) cells depends on the polarized activity of
a Ca 2+-sensitive K+ channel (IK channel; Pflügers Arch 432: R87–R93, 1996). This study …

Subcellular distribution of calcium‐sensitive potassium channels (IK1) in migrating cells

A Schwab, A Wulf, C Schulz, W Kessler… - Journal of cellular …, 2006 - Wiley Online Library
Cell migration is crucial for wound healing, immune defense, or formation of tumor
metastases. In addition to the cytoskeleton, Ca2+ sensitive K+ channels (IK1) are also part of …

Extracellular detection of K+ release during migration of transformed Madin-Darby canine kidney cells

T Danker, B Gaßner, H Oberleithner, A Schwab - Pflügers Archiv, 1996 - Springer
Madin Darby canine kidney cells transformed by alkaline stress (MDCK-F cells)
constitutively migrate at a rate of about 1 μm· min–1. Migration depends on the intermittent …

A role for K+ channels in cell proliferation

B Nilius, G Droogmans - Physiology, 1994 - journals.physiology.org
A Role for K+ Channels in Cell Proliferation Page 1 Differential activation of adenosine receptors
decreases N-type but potentiates Ptype Ca2+ current in hippocampal CA3 neurons. Neuron …

Plasticity of renal epithelial cells: the way a potassium channel supports migration.

A Schwab, H Oberleithner - Pflugers Archiv: European Journal of …, 1996 - europepmc.org
In this article we review aspects of plasticity of renal epithelial cells. We focus on one
particular feature, namely on cell migration. For normal renal and other epithelial cells …

K+ Channels and the Intracellular Calcium Signal in Human Melanoma Cell Proliferation

A Lepple-Wienhues, S Berweck, M Böhmig… - The Journal of …, 1996 - Springer
K+ channels, membrane voltage, and intracellular free Ca 2+ are involved in regulating
proliferation in a human melanoma cell line (SK MEL 28). Using patch-clamp techniques, we …

ET‐1 inhibits B‐16 murine melanoma cell migration by decreasing K+ currents

LY Liu, CL Hu, LJ Ma, ZH Zhang… - Cell motility and the …, 2004 - Wiley Online Library
Cell migration is mediated by ion channels and transporters, and plays crucial roles in a
variety of physiological and pathological processes. Previously, our studies have shown that …