We have developed a method which allows rapid and reproducible isolation of the
outermost layer of peripheral chromatin (cortical chromatin) from interphase HeLa cell …

The structure and the polypeptide composition of the nuclear shell isolated from interphase
HeLa cells have been investigated and compared to those of the intranuclear material. The …

We recently described the spontaneous dissociation from isolated HeLa cell chromatin of a
nuclear shell consisting of the outermost layer of peripheral chromatin and of fibrous lamina …

We have used high resolution scanning electron microscopy (SEM) to study the nuclear
envelope components of isolated mouse liver nuclei. The surfaces of intact nuclei are …

A quantitative ultrastructural analysis of the relationship between the invaginations formed
by the inner and outer membrane of the nuclear envelope and the nucleoli was performed in …

During the course of studies on the ultrastructure of a variety of tissues, we consistently
observed a structure at the periphery of the cell nucleus just beneath the inner nuclear …

Publisher Summary This chapter reviews the structural aspects and functional significance
of spatial relationship between the nucleolus and the nuclear envelope. The descriptive …

A number of recent studies have demonstrated a salt-, nuclease, and detergent-resistant
subnuclear structure termed the nuclear protein matrix which consists of a fibrogranular …

By defmition, the eukaryotic cell is characterized by a compartmentation structure that
divides the intracellular space into two different regions:(a) the nucleus, which contains the …

In the limited space of the nucleus, chromatin is organized in a dynamic and non-random
manner. Three ways of chromatin organization are compaction, formation of loops and the …