Viruses are intracellular pathogens that cause a vast array of diseases, which are often
severe and typified by high morbidity and mortality rates. Viral infections continue to be a …

Highlights•Antiviral innate immunity is regulated by changes in cellular proteins.•These
include changes in abundance, localisation, interaction and PTMs.•Viral immune evasion …

Viral infections are a major burden to human and animal health. Immune response against
viruses consists of innate and adaptive immunity which are both critical for the eradication of …

The increasing threat of bioterrorism and continued emergence of new infectious diseases
has driven a major resurgence in biomedical research efforts to develop improved …

ABSTRACT T cells must recognize pathogen-derived peptides bound to major
histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response …

Viruses have developed numerous and elegant strategies to manipulate the host cell
machinery to establish a productive infectious cycle. The interaction of viral proteins with …

Introduction Viruses induce profound changes in the cells they infect. Understanding these
perturbations will assist in designing better therapeutics to combat viral infection. System …

Recent years have witnessed the significant contribution of proteomics to understanding
important concepts in virology. Viruses have co-evolved with their hosts, acquiring …

Traditional vaccination, based on the core theory proposed by Louis Pasteur, has been
instrumental in increasing life expectancy and eradicating diseases. However, global …

Viruses constantly adapt to and modulate the host environment during replication and
propagation. Both DNA and RNA viruses encode multifunctional proteins that interact with …