Urinary 5-L-oxoproline was measured during normal pregnancies in Southampton, England
and Kingston, Jamaica. The CV of 5-L-oxoproline excretion in urine, determined over 7 d in …

The urinary excretion of 5‐oxoproline, which may be used as an index of glycine status, was
investigated in 30 normal pregnant women during different stages of pregnancy and in 18 …

1. The evidence is accumulating to suggest that glycine, the simplest amino acid, is
conditionally essential in man. Benzoic acid, by conjugation with glycine to form hippuric …

Urinary 5-L-oxoproline was measured in term and preterm infants from shortly after birth until
6 weeks of postnatal age to determine their ability to synthesise glycine. In term infants the …

A method for measuring 5-L-oxoproline in urine, which involves isolation by short-column
chromatography, acid hydrolysis to glutamic acid and enzymic assay of glutamic acid, was …

We hypothesized that a limitation in the endogenous formation of glycine might constrain
catch-up growth during recovery from severe childhood malnutrition. The urinary excretion of …

Materials and Methods Formimino-glutamic acid was estimated spectrophotometrically by
the method of Chanarin and Bennett (1962). Forty-five pregnant subjects less than 16 weeks …

In normal pregnancy amniotic fluid total hydroxyproline concentration rose to a peak around
the 28th week, before falling steadily to term while creatinine concentration was at first …

Abstract Of 15 English women in London and 260 Nigerian women in Ibadan, all with
megaloblastic anaemia of pregnancy, 7 and 5, respectively, excreted normal amounts of …

To learn more about the metabolic and clinical significance of 5-oxoproline (pyroglutamate,
pyrrolidone carboxylate), we investigated the blood plasma concentrations of 5-oxo-l-proline …