BT Roux, GS Cottrell - International Journal of Molecular Sciences, 2014 - mdpi.com
G protein-coupled receptors (GPCRs) are important cell signaling mediators, involved in essential physiological processes. GPCRs respond to a wide variety of ligands from light to …
CM Tang, PA Insel - Expert opinion on therapeutic targets, 2005 - Taylor & Francis
G-protein-coupled receptors (GPCRs), including 'orphan'GPCRs whose natural ligands are unknown, comprise the largest membrane receptor superfamily and are the most commonly …
PA Insel, CM Tang, I Hahntow, MC Michel - Biochimica et Biophysica Acta …, 2007 - Elsevier
By virtue of their large number, widespread distribution and important roles in cell physiology and biochemistry, G-protein-coupled receptors (GPCR) play multiple important …
T Schöneberg, A Schulz, H Biebermann… - Pharmacology & …, 2004 - Elsevier
G-protein-coupled receptors (GPCR) are involved in directly and indirectly controlling an extraordinary variety of physiological functions. Their key roles in cellular communication …
G protein coupled receptors (GPCR) constitute the largest group of cell surface receptors that transmit various signals across biological membranes through the binding and …
G Vauquelin, B Von Mentzer - 2008 - books.google.com
G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication …
Activating and inactivating mutations in numerous human G protein-coupled receptors (GPCRs) are associated with a wide range of disease phenotypes. Here we use several …
G protein–coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules. The notion that GPCRs also signal without an external chemical …
G-protein-coupled receptors (GPCRs) constitute the largest family of cell-surface molecules involved in signal transmission. These receptors play key physiological roles and their …