Sjögren's syndrome: shedding light on emerging and key drug targets

D Ridgewell, N Thalayasingam… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Sjögren's syndrome (SS) is an immune-mediated inflammatory condition
characterized by sicca syndrome, musculoskeletal pain, and fatigue. Extra-glandular …

[PDF][PDF] One year in review 2016: Sjögren's syndrome

F Ferro, R Vagelli, C Bruni, G Cafaro… - Clin Exp …, 2016 - clinexprheumatol.org
Sjögren's syndrome (SS) is a complex heterogeneous disease charactered by a broad
spectrum of clinical and serological manifestations, including non-Hodgkin's lymphoma …

An update of targeted therapeutic options for primary Sjögren syndrome: current status and future development

S Retamozo, A Sisó-Almirall… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Primary Sjögren syndrome (pSS) is a systemic autoimmune
disease that may affect 3 in 1,000 people within the general population. The therapeutic …

Treating the underlying pathophysiology of primary Sjögren syndrome: recent advances and future prospects

P Brito-Zerón, S Retamozo, H Gheitasi… - Drugs, 2016 - Springer
Sjögren Syndrome (SS) is a systemic autoimmune disease with a wide clinical spectrum that
extends from sicca symptoms of the mucosal surfaces to extra-glandular systemic …

Current and future therapies for primary Sjögren syndrome

R Seror, G Nocturne, X Mariette - Nature Reviews Rheumatology, 2021 - nature.com
Primary Sjögren syndrome (pSS) is a systemic autoimmune disease that is characterized by
a triad of symptoms that affect all patients (dryness, pain and fatigue). In addition, systemic …

Future treatments for Sjögren's syndrome

JO Pers, A Saraux - La Presse Médicale, 2016 - Elsevier
Primary Sjögren's syndrome (pSS) is a systemic multiorgan autoimmune disease that runs a
chronic progressive course. The recently developed treat-to-target paradigm involves …

[PDF][PDF] One year in review 2021: Sjögren's syndrome

G Cafaro, R Bursi, LG Chatzis, G Fulvio… - Clin Exp …, 2021 - clinexprheumatol.org
Sjögren's syndrome (SS) is a multifactorial systemic autoimmune disease of unknown
aetiology characterised by a wide spectrum of different clinical manifestations and scattered …

The pipeline of targeted therapies under clinical development for primary Sjögren's syndrome: a systematic review of trials

R Felten, F Scher, J Sibilia, JE Gottenberg… - Autoimmunity Reviews, 2019 - Elsevier
To date, no immunomodulatory drug has proved efficacious in primary Sjögren's syndrome
(pSS). In pSS, difficulties in drug efficacy assessment is related to the large spectrum of …

Emerging drugs for primary Sjögren's syndrome

S Gandolfo, S De Vita - Expert Opinion on Emerging Drugs, 2019 - Taylor & Francis
ABSTRACT Introduction: Primary Sjögren's syndrome (pSS) is an autoimmune systemic
disease characterized by a complex and not yet completely elucidated etiopathogenesis …

Update on the pathophysiology and treatment of primary Sjögren syndrome

C Baldini, G Fulvio, G La Rocca, F Ferro - Nature Reviews …, 2024 - nature.com
Sjögren syndrome or Sjögren disease is a chronic form of autoimmune epithelitis
characterized by lymphocytic infiltration of the exocrine glands, particularly the salivary and …