Galectin-9, a player in cytokine release syndrome and a surrogate diagnostic biomarker in SARS-CoV-2 infection

N Bozorgmehr, S Mashhouri, E Perez Rosero, L Xu… - MBio, 2021 - Am Soc Microbiol
The outbreak of SARS-CoV-2 infection has enormously impacted our lives. Clinical
evidence has implicated the emergence of cytokine release syndrome as the prominent …

[HTML][HTML] Galectin-3 as an important prognostic marker for COVID-19 severity

N Gajovic, SS Markovic, M Jurisevic, M Jovanovic… - Scientific Reports, 2023 - nature.com
Abstract Galectin-3 (Gal-3), multifunctional protein plays important roles in inflammatory
response, infection and fibrosis. The goal of study was to determine the association of Gal-3 …

[HTML][HTML] Immunopathology of galectin-3: an increasingly promising target in COVID-19

JL Caniglia, S Asuthkar, AJ Tsung, MR Guda… - …, 2020 - ncbi.nlm.nih.gov
The pandemic brought on by the outbreak of severe acute respiratory syndrome coronavirus
2 (SARS-CoV2) has become a global health crisis, with over 22 million confirmed cases and …

[PDF][PDF] Assessment of galectin-1, galectin-3, and PGE2 levels in patients with COVID-19

S Kazancioglu, FM Yilmaz, A Bastug, BO Ozbay… - Jpn J Infect Dis, 2021 - niid.go.jp
It is important to determine the inflammatory biomarkers in the severity of Coronavirus
Disease 2019 (COVID-19) with the emergence of the pandemic. Galectins and …

[HTML][HTML] Galectin-1 as the new player in staging and prognosis of COVID-19

SS Markovic, N Gajovic, M Jurisevic, M Jovanovic… - Scientific Reports, 2022 - nature.com
A new virus from the group of coronaviruses was identified as the cause of atypical
pneumonia and called Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) …

[HTML][HTML] A potential role for Galectin-3 inhibitors in the treatment of COVID-19

JL Caniglia, MR Guda, S Asuthkar, AJ Tsung… - PeerJ, 2020 - peerj.com
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), the
causative agent of coronavirus disease 2019 (COVID-19), has been declared a global …

[HTML][HTML] Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients

E Cervantes-Alvarez, NL la Rosa, MS la Mora… - Scientific Reports, 2022 - nature.com
Severe COVID-19 is associated with a systemic hyperinflammatory response leading to
acute respiratory distress syndrome (ARDS), multi-organ failure, and death. Galectin-3 is a ß …

[HTML][HTML] Hyperinflammation and fibrosis in severe COVID-19 patients: galectin-3, a target molecule to consider

J Garcia-Revilla, T Deierborg, JL Venero… - Frontiers in …, 2020 - frontiersin.org
COVID-19 disease have become so far the most important sanitary crisis in the XXI century.
In light of the events, any clinical resource should be considered to alleviate this crisis …

[HTML][HTML] Diagnostic significance of serum galectin-3 in hospitalized patients with COVID-19—A preliminary study

B Kuśnierz-Cabala, B Maziarz, P Dumnicka… - Biomolecules, 2021 - mdpi.com
Severe coronavirus disease 2019 (COVID-19) is associated with hyperinflammation leading
to organ injury, including respiratory failure. Galectin-3 was implicated in innate …

[HTML][HTML] Blood levels of galectin-9, an immuno-regulating molecule, reflect the severity for the acute and chronic infectious diseases

H Iwasaki-Hozumi, H Chagan-Yasutan, Y Ashino… - Biomolecules, 2021 - mdpi.com
Galectin-9 (Gal-9) is a β-galactoside-binding lectin capable of promoting or suppressing the
progression of infectious diseases. This protein is susceptible to cleavage of its linker …