The morphology of metaphase chromosome-derived chromatin fibers released from cells by
non-ionic detergent cell lysis in the presence of divalent cations has been studied by …

Metaphase chromosomes released from cells in the presence of Joklik's suspension media
by vortex-mixing with 0.5 mm glass beads have been analyzed by electron microscopy. In …

We have performed a very extensive electron microscopy investigation of the chromatin
structures extruded from partially denatured metaphase chromosomes from HeLa cells …

Electron micrographs of thin sections of metaphase chromosomes isolated from HeLa ceils
provide new insight into the higher-order arrangement of the nucleoprotein fiber …

Higher-order chromatin fibers (200--300 A in diameter) are reproducibly released from
nuclei after lysis in the absence of formalin and/or detergent. Electron microscope analysis …

Previous studies of the structure of metaphase chromosomes have relied heavily on electron
micrography and have revealed the existence of a 10-nm unit fiber that is thought to …

The higher-order assembly of the approximately 30 nm chromatin fibers into the
characteristic morphology of HeLa mitotic chromosomes was investigated by electron …

The organization of nucleosomes in higher order chromatin structures has been studied by
electron microscopy of chick red blood cell nuclei. Chromatin appears as a thick fiber with an …

Electron microscopy of HeLa metaphase nucleoids (ie whole metaphase cells exposed to 2
M salt and non-ionic detergent) spread by the Kleinschmidt technique, reveals a variety of …

When chromosome preparations made by the conventional air-drying method were
processed with the OsO 4/TCH technique and examined by scanning electron microscopy …