Aptamers: Promising Reagents in Biomedicine Application

H Zhou, Y Li, W Wu - Advanced Biology, 2024 - Wiley Online Library
Nucleic acid aptamers, often termed “chemical antibodies,” are short, single‐stranded DNA
or RNA molecules, which are selected by SELEX. In addition to their high specificity and …

Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

Nanotechnology and aptamers: applications in drug delivery

E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …

Development of aptamer-based nanomaterials for biological analysis

Y Pu, H Liu, B Liu, J Liao, J Liu… - Current Molecular …, 2013 - ingentaconnect.com
Aptamers selected from a large random sequence pool are oligonucleic acid or peptide
molecules that bind to a specific target molecule with high affinity and sensitivity. Targets …

Recent advancements of aptamers in cancer therapy

S Venkatesan, K Chanda, MM Balamurali - ACS omega, 2023 - ACS Publications
Aptamers are chemical antibodies possessing the capability of overcoming the limitations
posed by conventional antibodies, particularly for diagnostic, therapeutic, and theranostic …

Aptamers as versatile ligands for biomedical and pharmaceutical applications

B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
Aptamers are a class of targeting ligands that bind exclusively to biomarkers of interest.
Aptamers have been identified as candidates for the construction of various smart systems …

Status and prospects of aptamers as drug components

CMC Mattice, MC DeRosa - BioDrugs, 2015 - Springer
The unique properties of nucleic acid aptamers and their suitability to therapeutic
applications have attracted the attention of researchers for more than 2 decades. Aptamers …

[PDF][PDF] Aptamers as an emerging player in biology

M Iqbal - Aptamers Synth Antibodies, 2014 - researchgate.net
Aptamers are single stranded nucleic acid molecules that are considered as chemical rival
of antibodies. They are generated through an in vitro evolution process called SELEX …

Aptamers: molecular tools for medical diagnosis

V Cengiz Ozalp, M Kavruk, O Dilek… - Current topics in …, 2015 - ingentaconnect.com
Aptamers have been increasingly applied in biomedical field as a class of biorecognition
elements that possess many advantages such as high specificity and binding affinity, easy …

Aptamers: molecules of great potential

F Radom, PM Jurek, MP Mazurek, J Otlewski… - Biotechnology …, 2013 - Elsevier
Aptamers emerged over 20 years ago as a class of nucleic acids able to recognize specific
targets. Today, aptamer-related studies constitute a large and important field of …