To determine the size of the impairment across different cognitive domains in preclinical
Alzheimer's disease (AD), a meta-analysis based on 47 studies involving 9,097 controls and …

We review the literature on cognitive functioning during the transition from normal aging to
clinical Alzheimer's disease (AD). There is ample empirical evidence that deficits across …

Previous research suggests that patients with Alzheimer's disease exhibit cognitive
impairment in the years preceding a clinical diagnosis. Memory impairments are particularly …

Evidence from longitudinal, experimental, and neuroimaging studies converge to indicate
that psychological functions other than episodic memory are affected very early in the course …

Objective: To determine if individuals ultimately diagnosed with Alzheimer disease (AD)
exhibited evidence of cognitive impairment on neuropsychological tests administered …

The literature on cognitive markers in preclinical AD is reviewed. The findings demonstrate
that impairment in multiple cognitive domains is typically observed several years before …

A longitudinal study of asymptomatic individuals at risk of autosomal dominant familial
Alzheimer's disease was performed to assess the earliest clinical and neuropsychological …

Objectives To examine the ability of the total score and individual items from the Mini-Mental
State Examination in predicting the development of Alzheimer disease (AD) across a 3-and …

We investigated the influence of individual-difference variables implicated as risk factors for
Alzheimer's disease (AD) or known to be related to cognitive performance in normal aging …

• Although patients with Alzheimer's disease (AD) generally have impairments in multiple
areas of cognitive function, there are those patients who appear to have neuropsychological …