A series of novel compounds carrying 1, 2, 4-triazole scaffold was synthesized and
evaluated for their anticancer activity against a panel of cancer cell lines using MTT assay …

A new set of 1, 2, 3-triazoles was designed and synthesized to evaluate their potential to
inhibit the growth of cancer cells. Thiazole, thiazolone, and hydrazine as effective fragments …

Abstract Three novel series of 1, 2, 4‐triazole derivatives were designed and synthesized as
potential adenosine A2B receptor antagonists. The design of the new compounds depended …

Herein, we reported the synthesis of nineteen novel 1, 2, 4-triazole derivatives including 1, 3-
diphenyl-2-(1H-1, 2, 4-triazol-1-yl) propan-1-ones (7a-e), 1-(1, 3-diphenylpropan-2-yl)-1 H-1 …

Synthesis of bioactive heterocyclic compounds having effective biological activity is an
essential research area for wide-ranging applications. In this study, a conventional …

Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …

In this study, we researched the reactions of 5-(5-bromofuran-2-yl)-4-methyl-1, 2, 4-triazole-3-
thiol and 5-thiophene-(3-ylmethyl)-4R-1, 2, 4-triazole-3-thiols with some halogen-containing …

Background Triazole is an important heterocyclic moiety that occupies a unique position in
heterocyclic chemistry, due to its large number of biological activities. It exists in two isomeric …

In this study, a series of bis–and tetrakis–1, 2, 3–triazole derivatives were synthesized using
copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry in 73–95% yield. The …

To explore anticancer and antioxidant agents with improved potency, we synthesized a
series of amide linked 1, 4-disubstituted 1, 2, 3-triazoles through click chemistry approach …