[HTML][HTML] Galectin-3 activation and inhibition in heart failure and cardiovascular disease: an update

N Suthahar, WC Meijers, HHW Silljé, JE Ho, FT Liu… - Theranostics, 2018 - ncbi.nlm.nih.gov
Galectin-3 is a versatile protein orchestrating several physiological and pathophysiological
processes in the human body. In the last decade, considerable interest in galectin-3 has …

Galectin-3: a modifiable risk factor in heart failure

RA de Boer, AR van der Velde, C Mueller… - … drugs and therapy, 2014 - Springer
Myocardial galectin-3 is upregulated upon cardiac stressors such as angiotensin II and
pressure overload leading to cardiac remodeling and heart failure. The expression level of …

Galectin-3 in diabetic patients

G Pugliese, C Iacobini, C Ricci… - Clinical Chemistry and …, 2014 - degruyter.com
Galectin-3 is a versatile molecule which exerts several and sometimes opposite functions in
various pathophysiological processes. Recently, galectin-3 has gained attention as a …

Galectin‐3: a novel mediator of heart failure development and progression

RA de Boer, AA Voors, P Muntendam… - European journal of …, 2009 - Wiley Online Library
Galectins are a family of soluble β‐galactoside‐binding lectins that play many important
regulatory roles in inflammation, immunity, and cancer. Recently, a role for galectin‐3 in the …

The role of galectin‐3 in heart failure and cardiovascular disease

X Zhong, X Qian, G Chen… - Clinical and Experimental …, 2019 - Wiley Online Library
Summary Galectin‐3, a β‐galactoside‐binding lectin, is a new important player in the
progression of heart failure (HF) and is also linked to poor outcome in patients with …

The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

Galectin-3 in cardiac remodeling and heart failure

RA de Boer, L Yu, DJ van Veldhuisen - Current heart failure reports, 2010 - Springer
Galectin-3 is a member of the galectin family, which consists of animal lectins that bind β-
galactosides. Recently, a role for galectin-3 in the pathophysiology of heart failure has been …

Galectin-3: clinical utility and prognostic value in patients with heart failure

F Kramer - Research Reports in Clinical Cardiology, 2013 - Taylor & Francis
This review summarizes the key findings of 14 clinical trials in which Galectin-3 was
assessed as a biomarker of heart failure. In addition, most relevant information available …

[HTML][HTML] Galectin-3: a new biomarker for the diagnosis, analysis and prognosis of acute and chronic heart failure

N Hrynchyshyn, P Jourdain, M Desnos… - Archives of …, 2013 - Elsevier
Heart failure constitutes an important medical, social and economic problem. The
prevalence of heart failure is estimated as 2–3% of the adult population and increases with …

Galectin-3 in cardiovascular diseases

V Blanda, UM Bracale, MD Di Taranto… - International journal of …, 2020 - mdpi.com
Galectin-3 (Gal-3) is a β-galactoside-binding protein belonging to the lectin family with
pleiotropic regulatory activities and several physiological cellular functions, such as cellular …