[HTML][HTML] Curcumin attenuates chronic ethanol-induced liver injury by inhibition of oxidative stress via mitogen-activated protein kinase/nuclear factor E2-related factor 2 …

ZE Xiong, WG Dong, BY Wang, QY Tong… - Pharmacognosy …, 2015 - ncbi.nlm.nih.gov
Objective: This study aimed to investigate the protective effect of curcumin on chronic
ethanol-induced liver injury in mice and to explore its underlying mechanisms. Materials and …

Curcumin Decreased Oxidative Stress, Inhibited NF‐κB Activation, and Improved Liver Pathology in Ethanol‐Induced Liver Injury in Rats

S Samuhasaneeto, D Thong-Ngam… - BioMed Research …, 2009 - Wiley Online Library
To study the mechanism of curcumin‐attenuated inflammation and liver pathology in early
stage of alcoholic liver disease, female Sprague‐Dawley rats were divided into four groups …

[HTML][HTML] Protective effects of curcumin against chronic alcohol-induced liver injury in mice through modulating mitochondrial dysfunction and inhibiting endoplasmic …

B Wang, X Gao, B Liu, Y Li, M Bai, Z Zhang… - Food & Nutrition …, 2019 - ncbi.nlm.nih.gov
Background Curcumin is a major active ingredient extracted from powdered dry rhizome of
Curcuma longa. In Ayurveda and traditional Chinese medicine, it has been used as a …

Curcumin prevents chronic alcohol-induced liver disease involving decreasing ROS generation and enhancing antioxidative capacity

S Rong, Y Zhao, W Bao, X Xiao, D Wang, AK Nussler… - Phytomedicine, 2012 - Elsevier
Our previous study found that curcumin, a major active component of turmeric, could
ameliorate ethanol-induced hepatocytes oxidative stress in vitro. The objective of this work …

Curcumin alleviates ethanol-induced hepatocytes oxidative damage involving heme oxygenase-1 induction

W Bao, K Li, S Rong, P Yao, L Hao, C Ying… - Journal of …, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Curcumin is the main bioactive constituent
derived from the rhizome of turmeric (Curcuma longa Linn.), which has been used …

Negative effects of curcumin on liver injury induced by alcohol

HL Zhao, CH Song, OH Chai - Phytotherapy Research, 2012 - Wiley Online Library
Curcumin is known for its antiinflammatory and antifibrotic properties in liver damage.
However, the negative effects of curcumin on alcoholic liver damage are seldom reported. In …

Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK

HI Lee, RA McGregor, MS Choi, KI Seo, UJ Jung, J Yeo… - Life Sciences, 2013 - Elsevier
Aims This study investigated the hepatoprotective effects of low doses of curcumin against
liver damage induced by chronic alcohol intake and a high-fat diet. We also examined …

Curcumin and Baicalin ameliorate ethanol‐induced liver oxidative damage via the Nrf2/HO‐1 pathway

X Wang, X Chang, H Zhan, Q Zhang… - Journal of Food …, 2020 - Wiley Online Library
One of the key mechanisms of alcoholic liver disease is oxidative stress. Both Curcumin and
Baicalin exert antioxidant effects, but the mechanism of their combined effects of ethanol …

[HTML][HTML] Curcumin: reintroduced therapeutic agent from traditional medicine for alcoholic liver disease

HR Rahimi, MR Jaafari… - Asia Pacific Journal of …, 2015 - apjmt.mums.ac.ir
Alcoholic liver disease (ALD) is the main cause of chronic liver disease across the world and
can lead to fibrosis and cirrhosis. The etiopathogenesis of ALD is related to ethanol-induced …

[HTML][HTML] Curcumin can be acts as effective agent for prevent or treatment of alcohol-induced toxicity in hepatocytes: an illustrated mechanistic review

E Salehi, M Mashayekh, F Taheri… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Previous studies have shown that alcohol abuse can cause serious liver damage and
cirrhosis. The main pathway for these types of hepatocellular cell neurodegeneration is …