Lipidomics is a critical part of metabolomics and aims to study all the lipids within a living
system. We present here the development and evaluation of a sensitive capillary UPLC-MS …

Liquid chromatography–mass spectrometry (LC–MS) methods are most often used for
untargeted metabolomics and lipidomics. However, methods have not been standardized as …

The confident identification and in-depth profiling of molecular lipid species remain to be a
challenge in lipidomics analysis. In this work, an off-line two-dimensional mixed-mode and …

We propose a fully automated novel workflow for lipidomics based on flow injection,
followed by liquid chromatography–high-resolution mass spectrometry (FI/LC–HRMS). The …

Lipids have been analyzed in applications including drug discovery, disease etiology
elucidation, and natural products. The chemical and structural diversity of lipids requires a …

Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

Multidimensional chromatography offers enhanced chromatographic resolution and peak
capacity, which are crucial for analyzing complex samples. This study presents a novel …

Lipidomics is a subfield of metabolic phenotyping that focuses on high-throughput profiling
and quantification of lipids. Essential roles of lipidomics in translational and clinical research …

Exploratory or untargeted ultra performance liquid chromatography–mass spectrometry
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …

Lipid analysis at the molecular species level represents a valuable opportunity for clinical
applications due to the essential roles that lipids play in metabolic health. However, a …