The effects of increasing the frequency of pulsatile GnRH administration on LH and FSH
responsiveness were studied in five GnRH-deficient men who had achieved normal sex …

Normal pituitary and gonadal function can be maintained with long term pulsatile GnRH
administration in men with idiopathic hypogonadotropic hypogonadism (IHH), and both …

Previous investigations of the effects of GnRH on pituitary LH responses in normal men
required pharmacological doses of GnRH to avoid the confounding effects of endogenous …

To determine the role of testosterone (T) in modulating gonadotropin secretion during sexual
maturation, we studied males with isolated gonadotropin deficiency (IGD) before and during …

The effects of decreasing the frequency of pulsatile gonadotropin-releasing hormone
(GnRH) stimulation on pituitary responsiveness were studied in (a) men with isolated GnRH …

Patients who have severe hypogonadotropic hypogonadism caused by presumed
hypothalamic disease often have a subnormal LH response to a bolus dose of …

To examine the stimulus-secretion response of human pituitary gonadotrophs in vivo, we
applied a new multiple parameter deconvolution technique to analyze (1) exogenous GnRH …

Constant infusion of GnRH agonist (GnRH-A) leads to far greater suppression of
spermatogenesis and gonadotropins in the monkey than its intermittent administration. We …

The differential regulation of immunoactive FSH and LH secretion by endogenous GnRH
was studied using a GnRH antagonist,[Ac-D2Nal1, d4FPhe2, dTrp3, dArg6] GnRH (the NAL …

Gonadotropin-releasing hormone (GnRH) induces both synthesis and release of pituitary
gonadotropins, but rapid or slow frequencies of stimulation result in reduced LH and FSH …