Systematic review and meta-analysis of diagnostic biomarkers for pediatric pneumonia

LC Gunaratnam, JL Robinson… - Journal of the Pediatric …, 2021 - academic.oup.com
Background Pneumonia causes significant morbidity and mortality in children worldwide,
especially in resource-poor settings. Accurate identification of bacterial etiology leads to …

Combination of clinical symptoms and blood biomarkers can improve discrimination between bacterial or viral community-acquired pneumonia in children

MU Bhuiyan, CC Blyth, R West, J Lang… - BMC pulmonary …, 2019 - Springer
Background Differentiating bacterial from viral pneumonia is important for guiding targeted
management and judicious use of antibiotics. We assessed if clinical characteristics and …

Host inflammatory biomarkers of disease severity in pediatric community-acquired pneumonia: a systematic review and meta-analysis

CD Fernandes, MB Arriaga, MCM Costa… - Open Forum …, 2019 - academic.oup.com
Background Community-acquired pneumonia (CAP) is the leading cause of death in
children. Identification of reliable biomarkers offers the potential to develop a severity …

Clinical features and inflammatory markers in pediatric pneumonia: a prospective study

AS Berg, CS Inchley, HO Fjaerli, TM Leegaard… - European journal of …, 2017 - Springer
In this prospective, observational study on previously healthy children< 18 years, we aimed
to study the diagnostic ability of clinical features and inflammatory markers to (i) predict …

A three-step diagnosis of pediatric pneumonia at the emergency department using clinical predictors, C-reactive protein, and pneumococcal PCR

G Alcoba, K Keitel, V Maspoli, L Lacroix… - European journal of …, 2017 - Springer
Recommendations for the management of community-acquired pneumonia (CAP) advocate
that, in the absence of the clinical and laboratory findings typical of bacterial CAP, antibiotics …

Epidemiologic, clinical, and serum markers may improve discrimination between bacterial and viral etiologies of childhood pneumonia

H Farida, R Triasih, D Lokida, Y Mardian… - Frontiers in …, 2023 - frontiersin.org
Background Discrimination of bacterial and viral etiologies of childhood community-acquired
pneumonia (CAP) is often challenging. Unnecessary antibiotic administration exposes …

[HTML][HTML] Utility of inflammatory markers in predicting the aetiology of pneumonia in children

MA Elemraid, SP Rushton, MF Thomas… - … and infectious disease, 2014 - Elsevier
We aimed to investigate the diagnostic value of applying cut-off levels of inflammatory
markers and to develop a prediction model for differentiation between bacterial and viral …

Non‐specific host response markers in the differentiation between pneumococcal and viral pneumonia: What is the most accurate combination?

M Korppi - Pediatrics international, 2004 - Wiley Online Library
Background: Serum C‐reactive protein (CRP), blood white cell count (WBC), serum
procalcitonin (PCT) and erythrocyte sedimentation rate (ESR) were measured in 132 …

A systematic review on the diagnosis of pediatric bacterial pneumonia: when gold is bronze

T Lynch, L Bialy, JD Kellner, MH Osmond, TP Klassen… - PloS one, 2010 - journals.plos.org
Background In developing countries, pneumonia is one of the leading causes of death in
children under five years of age and hence timely and accurate diagnosis is critical. In North …

Diagnostic accuracy of routinely available biomarkers to predict bacteremia in children with community-acquired pneumonia: A Secondary analysis of the GPIP/ACTIV …

D Dudognon, C Levy, M Chalumeau, S Biscardi… - Frontiers in …, 2021 - frontiersin.org
Objective (s): Blood cultures (BC), when performed in children seen in the emergency
department with community-acquired pneumonia (CAP), are most of the time sterile. We …