Background Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis,
and yet the precise pathogenic mechanisms of peritoneal fibrosis remain unknown …

High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial
cells. Background Peritoneal fibrosis is a serious complication in long-term continuous …

One of the most common causes of peritoneal dialysis withdrawal is ultrafiltration failure
which is characterized by peritoneal membrane thickening and fibrosis. Although previous …

Background. Depending on the cytokine microenvironment, macrophages (Mφ) can adopt a
proinflammatory (M1) or a profibrotic (M2) phenotype characterized by the expression of cell …

The mechanism of peritoneal fibrosis in patients on continuous ambulatory peritoneal
dialysis (CAPD) is poorly elucidated. We investigated the cellular mechanism of high …

Background Peritoneal fibrosis is an essential precursor condition to the development of
encapsulating peritoneal sclerosis (EPS). This serious complication leads to a high mortality …

High glucose–induced PKC activation mediates TGF-β1 and fibronectin synthesis by
peritoneal mesothelial cells. Background Progressive peritoneal fibrosis, membrane …

Peritoneal fibrosis (PF), a serious pathophysiology of peritoneal dialysis (PD), is implicated
in various types of chronic inflammation. In the present study, we examined the benefits of …

It has been confirmed that alternatively activated macrophages (M2) participate in tissue
remodeling and fibrosis occurrence, but the effect of M2 on peritoneal fibrosis related to …

Peritoneal fibrosis remains a problem in kidney failure patients treated with peritoneal
dialysis. Severe peritoneal fibrosis with encapsulation or encapsulating peritoneal sclerosis …