Background: Sickle cell anaemia (SCA) is a major cause of morbidity and mortality in Africa
where there is no readily available effective treatment. This study was designed to determine …

Background Effective treatment and management of sickle cell disease (SCD) has been a
challenge in Africa over the years. Hematological parameters are very useful profiles in the …

Aim:-Elevated HbF, among other biological and environmental factors, is responsible for
decrease in mortality in sickle cell anaemia (SCA). This study determined the levels of HbF …

Backgroud: Sickle cell disease (SCD) is a more common and severe disease in Africa.
Nigeria the most populous black nation in Africa has the largest number of sickle cell …

Purpose To determine the neurological complications associated with sickle cell anaemia
(SCA) in Nigerians and evaluate the relative frequencies. Methodology Six-hundred-thirteen …

Background: Foetal haemoglobin has been implicated in the modulation of sickle cell crisis.
Its level is generally inversely proportional to the severity of sickle cell disease (SCD) for a …

Background The World Health Organization has declared Sickle Cell Anemia (SCA) a public
health priority. There are 300,000 births/year, over 75% in Africa, with estimates suggesting …

Background. South Africa has a low incidence of sickle cell disease (SCD). However, its
demographics are changing because of immigration from sub-Saharan African countries …

The hospital records of 62 Zambian children with sickle cell anaemia (SCA) who died during
a 3 year period (January 1987 to December 1989) at the Paediatric Wing of the University …

The hyperhemolysis paradigm that describes overlapping “hyperhemolytic-endothelial
dysfunction” and “high hemoglobin-hyperviscous” subphenotypes of sickle cell disease …