The murine septin4 gene (Sept4) has been implicated in diverse cellular functions, including
cytokinesis, apoptosis, and tumor suppression. Here, we investigated the function of Sept4 …

Septins belong to a family of polymerizing GTP-binding proteins that are required for many
cellular functions, such as membrane compartmentalization, vesicular trafficking, mitosis …

Septins are critical for numerous cellular processes through the formation of heteromeric
filaments and rings indicating the importance of structural regulators in septin assembly …

Since their essential role in cytokinesis was first shown in yeast, the septins have been
described to function in diverse cellular contexts. The members of this unique class of …

Septins are polymerizing GTP binding proteins required for cortical organization during
cytokinesis and other cellular processes. A mammalian septin gene Sept4 is expressed …

Septins are a family of GTP-binding proteins implicated in mammalian cell division. Most
studies examining the role of septins in this process have treated the family as a whole, thus …

Septins are members of the GTPase superfamily, which has been implicated in diverse
cellular functions including cytokinesis and morphogenesis. Septin 12 (SEPT12) is a testis …

Male infertility has become a worldwide health problem, but the etiologies of most cases are
still unknown. SEPT12, a GTP-binding protein, is involved in male fertility. Two SEPT12 …

In recent years a convergence of various aspects of cell biology has become apparent, and
yet investigators are only beginning to grasp the underlying unifying mechanisms. Among …

Septins are filamentous guanosine triphosphatase–binding proteins that are required for
cytokinesis in a wide range of organisms from yeast to man. Several septins, including …