Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and …

AJ Taylor, CD McClure, KA Shipkowski, EA Thompson… - PloS one, 2014 - journals.plos.org
Background Multi-walled carbon nanotubes (MWCNTs) pose a possible human health risk
for lung disease as a result of inhalation exposure. Mice exposed to MWCNTs develop …

Atomic layer deposition coating of carbon nanotubes with zinc oxide causes acute phase immune responses in human monocytes in vitro and in mice after pulmonary …

EC Dandley, AJ Taylor, KS Duke, MD Ihrie… - Particle and fibre …, 2015 - Springer
Background Atomic layer deposition (ALD) is a method for applying conformal nanoscale
coatings on three-dimensional structures. We hypothesized that surface functionalization of …

Functional consequences for primary human alveolar macrophages following treatment with long, but not short, multiwalled carbon nanotubes

S Sweeney, D Grandolfo… - International journal …, 2015 - Taylor & Francis
Purpose Multiwalled carbon nanotubes (MWCNTs) are a potential human health hazard,
primarily via inhalation. In the lung, alveolar macrophages (AMs) provide the first line of …

Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes

K Otsuka, K Yamada, Y Taquahashi, R Arakaki… - PLoS …, 2018 - journals.plos.org
Background Nanomaterials are widely used in various fields. Although the toxicity of carbon
nanotubes (CNTs) in pulmonary tissues has been demonstrated, the toxicological effect of …

Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes

MF Cesta, JP Ryman-Rasmussen… - American journal of …, 2010 - atsjournals.org
Engineered multi-walled carbon nanotubes (MWCNT) represent a possible health risk for
pulmonary fibrosis due to their fiber-like shape and potential for persistence in the lung. We …

Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis

J Dong, Q Ma - Nanotoxicology, 2018 - Taylor & Francis
Pulmonary exposure to carbon nanotubes (CNTs) induces fibrosing lesions in the lungs that
manifest rapid-onset inflammatory and fibrotic responses, leading to chronic fibrosis in …

Multiwall carbon nanotubes mediate macrophage activation and promote pulmonary fibrosis through TGF‐β/Smad signaling pathway

P Wang, X Nie, Y Wang, Y Li, C Ge, L Zhang, L Wang… - Small, 2013 - Wiley Online Library
Multiwall carbon nanotubes (MWCNTs) have been widely used in many disciplines due to
their unique physical and chemical properties, but have also raised great concerns about …

Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice

X Wang, P Katwa, R Podila, P Chen, PC Ke… - Particle and fibre …, 2011 - Springer
Background Multi-walled carbon nanotubes (MWCNTs) are widely used in many disciplines
due to their unique physical and chemical properties. Therefore, some concerns about the …

Pathologic and molecular profiling of rapid-onset fibrosis and inflammation induced by multi-walled carbon nanotubes

J Dong, DW Porter, LA Batteli, MG Wolfarth… - Archives of …, 2015 - Springer
Multi-walled carbon nanotubes (MWCNT) are new materials with a wide range of industrial
and commercial applications. However, their nano-scaled size and fiber-like shape render …

Role of A2B adenosine receptor-dependent adenosine signaling in multi-walled carbon nanotube-triggered lung fibrosis in mice

B Liu, Q Bing, S Li, B Han, J Lu, R Baiyun… - Journal of …, 2019 - Springer
Background Multi-walled carbon nanotube (MWCNT)-induced lung fibrosis leads to health
concerns in human. However, the mechanisms underlying fibrosis pathogenesis remains …