Nuclear envelope-limited chromatin sheets (ELCS) form during excessive interphase
nuclear envelope growth in a variety of cells. ELCS appear as extended sheets within the …

Abstract “Interphase epichromatin” describes the surface of chromatin located adjacent to
the interphase nuclear envelope. It was discovered in 2011 using a bivalent anti …

The interphase nucleus and nuclear envelope can acquire a myriad of shapes in normal or
pathological cell states. There exist a wide variety of indentations and invaginations, of …

Nuclear envelope-limited chromatin sheets (ELCS) are enigmatic membranous structures of
uncertain function. This study describes the induction of ELCS in p53 mutated Burkitt's …

Chromatin gels, metaphase chromosomes, and intact nuclei were studied by freeze
fracturing followed by electron microscopy. The results complement and extend those …

Cryoelectron microscopy of vitrified sections has become a powerful tool for investigating the
fine structural features of cellular compartments. In the present study, this approach has …

We have developed a method which allows rapid and reproducible isolation of the
outermost layer of peripheral chromatin (cortical chromatin) from interphase HeLa cell …

The use of imaging techniques has become an essential tool in cell biology. In particular,
advances in fluorescence microscopy and conventional transmission electron microscopy …

The presence and folding pattern of chromatin in eukaryotic cells remain elusive and
controversial. In this study, we prepared ultra-thin sections of Hela cells with three different …

Highlights•Cryo-electro microscopy reveals the native conformation of chromatin fiber both
in vitro and in situ.•Presence of linker histone and ionic conditions determines the level of …