The intention of this review is to stress new information regarding the quite versatile
functions of Kupffer cells. Although their main function is phagocytosis and defence of the …

Kupffer cells are hepatic macrophages that reside in the lumen of hepatic sinusoids (Fig. 1).
They lie on or between the endothelial cells and have cytoplasmic extensions into the …

Kupffer cells, the resident liver macrophages have long been considered as mostly
scavenger cells responsible for removing particulate material from the portal circulation …

Classically, the maintenance and control of liver homeostasis are assigned to the metabolic
activity of parenchymal cells. However, recent evidence highlights complex and tightly …

Carl von Kupffer first described Kupffer cells, the star-shaped fixed macrophages of the liver,
in 1898 (1). Most of the studies to date have focused either on structure or isolation of …

Kupffer cells are resident liver macrophages and play a critical role in maintaining liver
functions. Under physiological conditions, they are the first innate immune cells and protect …

Kupffer cells are mononuclear phagocytes that reside within the sinusoids of the liver.
Historically, these hepatic macrophages have been regarded as having only a limited …

Kupffer cells (KC), the resident liver macrophages, constitute the liver sinusoids together
with other cells such as sinusoidal endothelial cells, hepatic stellate cells, liver-specific …

Kupffer cells (KC) constitute 80–90% of the tissue macrophages present in the body. They
reside within the lumen of the liver sinusoids, and are therefore constantly exposed to gut …

Publisher Summary The study of Kupffer cells has developed rapidly and has been
extended to problems concerning the origin, structure, and function of these cells in normal …