Tailored extraction procedure is required to ensure recovery of the main lipid classes in whole blood when profiling the lipidome of dried blood spots

JJ Aristizabal Henao, AH Metherel, RW Smith… - Analytical …, 2016 - ACS Publications
The use of dried blood spots has increased in research and clinical settings recently,
particularly in field studies and screening, but comprehensive acyl-specific lipidomic …

Lipid extraction from dried blood spots and dried milk spots for untargeted high throughput lipidomics

S Furse, A Koulman - Molecular Omics, 2020 - pubs.rsc.org
Dried blood spots (DBS) and dried milk spots (DMS) represent convenient matrices for
collecting and storing human samples. However, the use of these sample types for …

Untargeted lipidomic profiling of dry blood spots using SFC-HRMS

P Le Faouder, J Soullier, M Tremblay-Franco… - Metabolites, 2021 - mdpi.com
Lipids are essential cellular constituents that have many critical roles in physiological
functions. They are notably involved in energy storage and cell signaling as second …

Dried blood spots in clinical lipidomics: optimization and recent findings

HB Ferreira, IMS Guerra, T Melo, H Rocha… - Analytical and …, 2022 - Springer
Dried blood spots (DBS) are being considered as an alternative sampling method of blood
collection that can be used in combination with lipidomic and other omic analysis. DBS are …

[HTML][HTML] Dried Blood Spot Microsampling: A Semi-Quantitative 4D-Lipidomics Approach Using Ultra High Performance Liquid Chromatography-High Resolution Mass …

JL Roberts, MJ Ryan, L Whiley, M Gay, V Nambiar… - Talanta, 2025 - Elsevier
Dried blood spot (DBS) sample collections can offer a minimally invasive, cost-effective
alternative to traditional venepuncture for remote sampling and high-frequency metabolic …

Comparing identified and statistically significant lipids and polar metabolites in 15‐year old serum and dried blood spot samples for longitudinal studies

JE Kyle, CP Casey, KG Stratton, EM Zink… - … in mass spectrometry, 2017 - Wiley Online Library
Rationale The use of dried blood spots (DBS) has many advantages over traditional plasma
and serum samples such as the smaller blood volume required, storage at room …

Dynamic and temporal assessment of human dried blood spot MS/MSALL shotgun lipidomics analysis

F Gao, J McDaniel, EY Chen, HE Rockwell… - Nutrition & …, 2017 - Springer
Background Real-time and dynamic assessment of an individual's lipid homeostatic state in
blood is complicated due to the need to collect samples in a clinical environment. In the …

Comprehensive lipidomic profiling by plasma separation cards

LM Bishop, O Fiehn - Analytical and bioanalytical chemistry, 2023 - Springer
Large-scale lipidomic analyses have been limited by the cost and accessibility of traditional
venipuncture sampling. Microsampling techniques offer a less-invasive and more accessible …

Extraction of lipids from liquid biological samples for high-throughput lipidomics

S Furse, AJ Watkins, A Koulman - Molecules, 2020 - mdpi.com
Extraction of the lipid fraction is a key part of acquiring lipidomics data. High-throughput
lipidomics, the extraction of samples in 96w plates that are then run on 96 or 384w plates …

Benchmarking one-phase lipid extractions for plasma lipidomics

M Höring, C Stieglmeier, K Schnabel… - Analytical …, 2022 - ACS Publications
A key element of successful lipidomics analysis is a sufficient extraction of lipid molecules
typically by two-phase systems such as chloroform-based Bligh and Dyer (B&D). However …