Recent evidence indicates that neuropathic pain from partial peripheral nerve injury is
maintained by electrophysiologically abnormal signals from injured sensory neurons. To …

The spontaneous, ectopic activity in sensory nerves that is induced by peripheral nerve
injury is thought to contribute to the generation of “neuropathic” pain in humans. To examine …

We examined whether signals from the neuroma or the dorsal root ganglion of the injured
segment are critical for the generation of neuropathic pain. To this aim, we used a rat model …

Zhang, Jun-Ming, David F. Donnelly, Xue-Jun Song, and Robert H. LaMotte. Axotomy
increases the excitability of dorsal root ganglion cells with unmyelinated axons. J …

Although it is generally thought that sensory transduction occurs at or close to peripheral
nerve endings, with action potentials subsequently propagating along the axons of dorsal …

1 Functional reorganization of sensory pathways in the rat spinal dorsal horn following
sciatic nerve transection was examined using spinal cord slices with an attached dorsal root …

Primary sensory neurons with myelinated axons were examined in vitro in excised whole
lumbar dorsal root ganglia (DRGs) taken from adult rats up to 9 days after tight ligation and …

FOLLOWING nerve injury, modified somatic ion channels may underlie ectopic activity in
axotomized A-type neurones in dorsal root ganglia (DRGs) leading to abnormal pain …

We investigated electrophysiological changes in chronically axotomized and neighboring
intact dorsal root ganglion (DRG) neurons in rats after either a peripheral axotomy consisting …

A chronic compression of the dorsal root ganglion (CCD) produces ipsilateral cutaneous
hyperalgesia and allodynia in rats. Intracellular electrophysiological recordings from …