Salmonella‐Containing Vacuoles: Directing Traffic and Nesting to Grow

MA Bakowski, V Braun, JH Brumell - Traffic, 2008 - Wiley Online Library
Salmonella enterica serovar Typhimurium (S. typhimurium) is a gram‐negative facultative
intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion …

The Virulence Protein SopD2 Regulates Membrane Dynamics of Salmonella-Containing Vacuoles

N Schroeder, T Henry, C de Chastellier, W Zhao… - PLoS …, 2010 - journals.plos.org
Salmonella enterica serovar Typhimurium is a Gram-negative bacterial pathogen causing
gastroenteritis in humans and a systemic typhoid-like illness in mice. The capacity of …

SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole

N Lau, AL Haeberle, BJ O'Keeffe, EA Latomanski… - PLoS …, 2019 - journals.plos.org
The enteric bacterial pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium),
utilizes two type III secretion systems (T3SSs) to invade host cells, survive and replicate …

Multiple Salmonella-pathogenicity island 2 effectors are required to facilitate bacterial establishment of its intracellular niche and virulence

K Knuff-Janzen, A Tupin, S Yurist-Doutsch… - PLoS …, 2020 - journals.plos.org
The pathogenesis of Salmonella Typhimurium depends on the bacterium's ability to survive
and replicate within host cells. The formation and maintenance of a unique membrane …

SopD2 is a Novel Type III Secreted Effector of Salmonella typhimurium That Targets Late Endocytic Compartments Upon Delivery Into Host Cells

JH Brumell, S Kujat‐Choy, NF Brown, BA Vallance… - Traffic, 2003 - Wiley Online Library
Salmonella typhimuriumis a facultative intracellular pathogen that utilizes two type III
secretion systems to deliver virulence proteins into host cells. These proteins, termed …

[HTML][HTML] Maturation steps of the Salmonella-containing vacuole

JP Gorvel, S Méresse - Microbes and infection, 2001 - Elsevier
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Salmonella SPI1 effector SipA persists after entry and cooperates with a SPI2 effector to regulate phagosome maturation and intracellular replication

LC Brawn, RD Hayward, V Koronakis - Cell host & microbe, 2007 - cell.com
Salmonellae employ two type III secretion systems (T3SSs), SPI1 and SPI2, to deliver
virulence effectors into mammalian cells. SPI1 effectors, including actin-binding SipA, trigger …

The Salmonella enterica Serovar Typhimurium Translocated Effectors SseJ and SifB Are Targeted to the Salmonella-Containing Vacuole

JA Freeman, ME Ohl, SI Miller - Infection and immunity, 2003 - Am Soc Microbiol
ABSTRACT The Salmonella enterica serovar Typhimurium type III secretion system (TTSS)
encoded in Salmonella pathogenicity island 2 (SPI-2) promotes replication within host cells …

Disruption of the Salmonella-Containing Vacuole Leads to Increased Replication of Salmonella enterica Serovar Typhimurium in the Cytosol of Epithelial Cells

JH Brumell, P Tang, ML Zaharik… - Infection and immunity, 2002 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that inhabits
a vacuolar compartment, called the Salmonella-containing vacuole (SCV), in infected host …

Attenuated Salmonella Typhimurium Lacking the Pathogenicity Island-2 Type 3 Secretion System Grow to High Bacterial Numbers inside Phagocytes in Mice

AJ Grant, FJE Morgan, TJ McKinley, GL Foster… - PLoS …, 2012 - journals.plos.org
Intracellular replication within specialized vacuoles and cell-to-cell spread in the tissue are
essential for the virulence of Salmonella enterica. By observing infection dynamics at the …