Nonsteroidal anti-inflammatory drugs are widely used and prescribed in the United States.
Between 35 and 70 million prescriptions for nonsteroidal anti-inflammatory drugs are written …

The use of the new selective cyclooxygenase-2 (COX-2) inhibitors (such as celecoxib and
rofecoxib) for the treatment of pain and inflammation caused by fractures, cementless total …

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are being increasingly
employed as a part of multimodal non-opioid strategies to treat postoperative pain. In the …

Prostaglandins are important mediators of bone repair, and cyclooxygenases are required
for prostaglandin production. Data from animal studies suggest that both non-specific and …

Nonsteroidal anti‐inflammatory drugs (NSAIDs) are among the most prescribed
pharmacologic agents in medicine. The ability of these drugs to decrease inflammation is …

Nonsteroidal anti-inflammatory drugs (NSAIDs) lead to severe and unpredictable side
effects that are costly for individuals and the economy overall. As baby boomers enter their …

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed medications for relief
of pain and inflammation. Recent animal studies using models of fracture healing and bone …

In the study reported here, we determined the effects on bone healing of rofecoxib, one of
the selective cyclooxygenase-2 (Cox-2) inhibitors that has been used for postsurgical …

Prostaglandins (PGs) are released as part of the inflammatory response. They are
synthesised from arachidonic acid by the cyclooxygenase enzymes, COX-1 and-2. NSAIDS …

Abstract Purpose Non-selective (NSAIDs) and selective (COX-2) nonsteroidal anti-
inflammatory drugs are commonly used for their analgesic and anti-inflammatory effects …