Lipids are critical for maintaining homeostasis and cellular metabolism. However, the
dysregulation of lipid metabolism contributes to the pathogenesis of chronic inflammatory …

The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3)
is activated constitutively in a wide array of human cancers. It is an appealing molecular …

Cancer remains a significant global health concern. The dysregulation of signaling networks
in tumor cells greatly affects their functions. This review intends to explore phytochemicals …

Simple Summary Lipid metabolism involves signalling pathways that control the uptake,
synthesis, and breakdown of lipid molecules. This highly controlled system is dysregulated …

Cancer has become one of the most multifaceted and widespread illnesses affecting human
health, causing substantial mortality at an alarming rate. After cardiovascular problems, the …

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in signal
transmission from the plasma membrane to the nucleus, regulating the expression of genes …

Signal transducer and activator of transcription 3 (STAT3) is a transcriptional factor involved
in almost all cancer hallmark features including tumor proliferation, metastasis …

In the tumor microenvironment, cytokines, growth factors, and oncogenes mediate
constitutive activation of the signal transducer and activator of transcription 3 (STAT3) …

The reprogramming of lipid metabolism and its association with oncogenic signaling
pathways within the tumor microenvironment (TME) have emerged as significant hallmarks …

Reprogrammed metabolism is a hallmark of cancer. However, the metabolic dependency of
cancer, from tumour initiation through disease progression and therapy resistance, requires …