NDM-35-Producing ST167 Escherichia coli Highly Resistant to β-Lactams Including Cefiderocol

L Poirel, JM Ortiz de la Rosa, Z Sakaoglu… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
ABSTRACT A multidrug-resistant (carbapenems, aztreonam+ avibactam, and cefiderocol)
ST167 Escherichia coli clinical isolate recovered from a patient hospitalized in Switzerland …

An NDM-Producing Escherichia coli Clinical Isolate Exhibiting Resistance to Cefiderocol and the Combination of Ceftazidime-Avibactam and Aztreonam: Another …

PJ Simner, Y Bergman, R Conzemius… - Open Forum …, 2023 - academic.oup.com
Background Cefiderocol and ceftazidime-avibactam plus aztreonam (CZA-ATM) are
preferred treatment regimens for New Delhi metallo-β-lactamase (NDM)-producing …

Rapid selection of a cefiderocol-resistant Escherichia coli producing NDM-5 associated with a single amino acid substitution in the CirA siderophore receptor

AB Jousset, C Poignon, S Yilmaz… - Journal of …, 2023 - academic.oup.com
Cefiderocol is a novel siderophore-conjugated cephalosporin that is very promising for the
treatment of infections caused by MDR bacteria. Its main advantages reside in its stability …

[HTML][HTML] Population Analysis of Escherichia coli Sequence Type 361 and Reduced Cefiderocol Susceptibility, France

AB Jousset, L Bouabdallah, A Birer… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Cefiderocol resistance is increasingly reported in New Delhi metallo-β-lactamase–
producing Enterobacterales. Genomic and phenotypic analysis of Escherichia coli sequence …

Occurrence of high levels of cefiderocol resistance in carbapenem-resistant Escherichia coli before its approval in China: a report from China CRE-network

Q Wang, L Jin, S Sun, Y Yin, R Wang, F Chen… - Microbiology …, 2022 - Am Soc Microbiol
Cefiderocol has been approved in the United States and Europe but not in China. We aim to
evaluate carbapenem-resistant Enterobacterales (CRE) susceptibility to cefiderocol to …

In Vitro Activity of Cefiderocol Against Meropenem-Nonsusceptible Gram-Negative Bacilli with Defined β-Lactamase Carriage: SIDERO-WT Surveillance Studies …

MG Wise, JA Karlowsky, MA Hackel… - Microbial Drug …, 2023 - liebertpub.com
We examined the in vitro susceptibility of meropenem-nonsusceptible Enterobacterales,
Pseudomonas aeruginosa, and Acinetobacter baumannii complex isolates from five …

The acquisition of transferable extrachromosomal fec operon is associated with a cefiderocol MIC increase in Enterobacterales

K Kocer, S Boutin, K Heeg… - Journal of Antimicrobial …, 2022 - academic.oup.com
Background Cefiderocol is a novel siderophore cephalosporin active against MDR Gram-
negative bacilli, including MBL-harbouring Enterobacterales. The detection of multiple …

Progressive Development of Cefiderocol Resistance in Escherichia coli During Therapy is Associated With an Increase in blaNDM-5 Copy Number and Gene …

PJ Simner, HH Mostafa, Y Bergman… - Clinical Infectious …, 2022 - academic.oup.com
Background As cefiderocol is increasingly being prescribed in clinical practice, it is critical
that we understand key mechanisms contributing to acquired resistance to this agent …

New Delhi metallo-beta-lactamase facilitates the emergence of cefiderocol resistance in Enterobacter cloacae

D Nurjadi, K Kocer, Q Chanthalangsy… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Cefiderocol is a promising novel siderophore cephalosporin for the treatment of multidrug-
resistant Gram-negative bacilli and with stability against degradation by metallo-β …

In vitro antibacterial activity of cefiderocol against recent multidrug-resistant carbapenem-nonsusceptible Enterobacterales isolates

Q Zhang, N Neidig, TY Chu, C Divoky… - … and infectious disease, 2022 - Elsevier
Cefiderocol, a siderophore-containing cephalosporin with broad-spectrum antimicrobial
activity against many β-lactam-resistant Gram-negative bacteria, was tested by broth …