Spontaneous periodic episodes of hypothermia still defy medical knowledge. In 1969,
Shapiro et al. described the first two cases of spontaneous periodic hypothermia associated …

Unprovoked hypothermia is an unusual presenting sign. When occurring with diaphoresis it
has been referred to as episodic spontaneous hypothermia with hyperhidrosis. Earlier …

Episodic hyperhidrosis and hypothermia are the primary symptoms of a rare central nervous
system disorder of thermoregulation which is often associated with agenesis of the corpus …

Episodic spontaneous hypothermia is an infrequent disorder, with unknown pathogenic
mechanisms. A systemic cause or underlying brain lesion has not been found for the …

Objective: Investigation of the mechanism of the idiopathic periodic hyperthermia associated
with agenesis of the corpus callosum. Setting: Tertiary care referral center. Patient: Fourteen …

Methods Case series of spontaneous hypothermia in adults, from a register of the French
Society of Internal Medicine (SNFMI). Results The ten collected cases of spontaneous …

• A patient with episodic hypothermia and agenesis of the corpus callosum had no direct
evidence of hypothalamic-pitultary dysfunction. However, it is speculated on the basis of a …

We present a patient diagnosed with Shapiro syndrome without corpus callosum agenesis.
A 4-year-old-girl was admitted to the hospital with complaints of sweating, cooling, and …

Hypothermia, defined as a core temperature below 35° C, can occur in a variety of clinical
settings, including environmental exposure, shock, infection, metabolic disorders (such as …

Spontaneous recurrent hypothermia and hyperhidrosis associated with agenesis of the
corpus callosum was first described by Shapiro and Plum in 1967. Since then, several cases …