Study of the allergenic potential of Bacillus thuringiensis Cry1Ac toxin following intra-gastric administration in a murine model of food-allergy

KI Santos-Vigil, D Ilhuicatzi-Alvarado… - International …, 2018 - Elsevier
Abstract Cry1Ac toxin, from Bacillus thuringiensis, is widely used as a biopesticide and
expressed in genetically modified (GM) plants used for human and animal consumption …

Intragastric and intraperitoneal administration of Cry1Ac protoxin from Bacillus thuringiensis induces systemic and mucosal antibody responses in mice

RI Vazquez-Padron, L Moreno-Fierros, L Neri-Bazán… - Life Sciences, 1999 - Elsevier
The spore-forming soil bacterium Bacillus thuringiensis produces parasporal inclusion
bodies composed by δ-endotoxins also known as Cry proteins, whose resistance to …

Comparative study of the adjuvanticity of Bacillus thuringiensis Cry1Ab protein and cholera toxin on allergic sensitisation and elicitation to peanut

VD Guimaraes, MF Drumare, S Ah-Leung… - Food and Agricultural …, 2008 - Taylor & Francis
We aimed to investigate the adjuvanticity of Cry1Ab on allergic sensitisation and elicitation
to peanut in mice, in comparison with cholera toxin (CT), a known mucosal Th2 adjuvant …

Bacillus thuringiensis Cry1Ac Protoxin is a Potent Systemic and Mucosal Adjuvant

VÁZQUEZ, R DE LA - Scandinavian journal of immunology, 1999 - Wiley Online Library
Recently we demonstrated that recombinant Cry1Ac protoxin from Bacillus thuringiensis is a
potent systemic and mucosal immunogen. In this study we compared the adjuvant effects of …

[HTML][HTML] Intranasal, rectal and intraperitoneal immunization with protoxin Cry1Ac from Bacillus thuringiensis induces compartmentalized serum, intestinal, vaginal and …

L Moreno-Fierros, N García, R Gutiérrez… - Microbes and …, 2000 - Elsevier
Recently we discovered that the Cry1Ac protoxin of Bacillus thuringiensis administered to
Balb/c mice intraperitoneally (ip) or intragastrically is a systemic and intestinal immunogen …

Immunization with Cry1Ac from Bacillus Thuringiensis Increases Intestinal IgG Response and Induces the Expression of FcRn in the Intestinal Epithelium of Adult …

SL Verdin‐Terán, A Vilches‐Flores… - Scandinavian …, 2009 - Wiley Online Library
We have shown that Cry1Ac protoxin from Bacillus thuringiensis is a potent mucosal and
systemic immunogen with adjuvant properties. Interestingly, we have observed that Cry1Ac …

Characterization of the mucosal and systemic immune response induced by Cry1Ac protein from Bacillus thuringiensis HD 73 in mice

RI Vazquez-Padron, L Moreno-Fierros… - Brazilian Journal of …, 2000 - SciELO Brasil
The present paper describes important features of the immune response induced by the
Cry1Ac protein from Bacillus thuringiensis in mice. The kinetics of induction of serum and …

Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice

M Andreassen, T Bøhn, OG Wikmark, J Bodin… - BMC immunology, 2016 - Springer
Background In genetically modified (GM) crops there is a risk that the inserted genes may
introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize …

Cry1Ab Protein from Bacillus thuringiensis and MON810 cry1Ab‐transgenic Maize Exerts No Adjuvant Effect After Airway Exposure

M Andreassen, T Bøhn, OG Wikmark… - Scandinavian …, 2015 - Wiley Online Library
The genetically modified (GM) maize event MON 810 has been inserted with a processed
version of the transgene, cry1Ab, derived from the soil bacterium Bacillus thuringiensis (Bt) …

Humoral and cellular immune responses in mice after airway administration of Bacillus thuringiensis Cry1Ab and MON810 cry1Ab-transgenic maize

M Andreassen, E Rocca, T Bøhn… - Food and Agricultural …, 2015 - Taylor & Francis
Genetically modified (GM) crops may bring new proteins with immunogenic and allergenic
properties into the food and feed chains. The most commonly grown GM maize, MON810 …