Bilayers of nucleosome core particles

A Leforestier, J Dubochet, F Livolant - Biophysical journal, 2001 - cell.com
Among the multiple effects involved in chromatin condensation and decondensation
processes, interactions between nucleosome core particles are suspected to play a crucial …

Liquid crystalline ordering of nucleosome core particles under macromolecular crowding conditions: evidence for a discotic columnar hexagonal phase

A Leforestier, F Livolant - Biophysical journal, 1997 - cell.com
Macromolecular crowding conditions occurring inside the cell nucleus were reproduced
experimentally with solutions of mononucleosome core particles to study their …

Phase diagram of nucleosome core particles

S Mangenot, A Leforestier, D Durand… - Journal of molecular …, 2003 - Elsevier
We present a phase diagram of the nucleosome core particle (NCP) as a function of the
monovalent salt concentration and applied osmotic pressure. Above a critical pressure …

Structure and phase diagram of nucleosome core particles aggregated by multivalent cations

A Bertin, S Mangenot, M Renouard, D Durand… - Biophysical journal, 2007 - cell.com
The degree of compaction of the eukaryotic chromatin in vivo and in vitro is highly sensitive
to the ionic environment. We address the question of the effect of multivalent ions on the …

The influence of ionic environment and histone tails on columnar order of nucleosome core particles

NV Berezhnoy, Y Liu, A Allahverdi, R Yang, CJ Su… - Biophysical journal, 2016 - cell.com
The nucleosome core particle (NCP) is the basic building block of chromatin. Nucleosome-
nucleosome interactions are instrumental in chromatin compaction, and understanding NCP …

Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

J Bednar, RA Horowitz, SA Grigoryev… - Proceedings of the …, 1998 - National Acad Sciences
The compaction level of arrays of nucleosomes may be understood in terms of the balance
between the self-repulsion of DNA (principally linker DNA) and countering factors including …

Nucleosome conformational variability in solution and in interphase nuclei evidenced by cryo-electron microscopy of vitreous sections

M Eltsov, D Grewe, N Lemercier… - Nucleic acids …, 2018 - academic.oup.com
In Eukaryotes, DNA is wound around the histone octamer forming the basic chromatin unit,
the nucleosome. Atomic structures have been obtained from crystallography and single …

Are liquid crystalline properties of nucleosomes involved in chromosome structure and dynamics?

F Livolant, S Mangenot… - … of the Royal …, 2006 - royalsocietypublishing.org
Nucleosome core particles correspond to the structural units of eukaryotic chromatin. They
are charged colloids, 101 Å in diameter and 55 Å in length, formed by the coiling of a …

Tail-induced attraction between nucleosome core particles

F Mühlbacher, H Schiessel, C Holm - … E—Statistical, Nonlinear, and Soft Matter …, 2006 - APS
We study a possible electrostatic mechanism underlying the compaction of DNA inside the
nuclei of eucaryotes: the tail-bridging effect between nucleosomes, the fundamental DNA …

Layering, bundling, and azimuthal orientations in dense phases of nucleosome core particles

AG Cherstvy, R Everaers - Journal of Physics: Condensed Matter, 2006 - iopscience.iop.org
We propose an idea how the helical pattern of charges on the surface of DNA can affect
electrostatic interactions of nucleosome core particles in their columnar and crystalline …