Plasticity of renal epithelial cells: the way a potassium channel supports migration.

A Schwab, H Oberleithner - Pflugers Archiv: European Journal of …, 1996 - europepmc.org
In this article we review aspects of plasticity of renal epithelial cells. We focus on one
particular feature, namely on cell migration. For normal renal and other epithelial cells …

Volume dynamics in migrating epithelial cells measured with atomic force microscopy

SW Schneider, P Pagel, C Rotsch, T Danker… - Pflügers Archiv, 2000 - Springer
Migration of transformed renal epithelial cells (transformed Madin-Darby canine kidney cells,
MDCK-F cells) relies on the activity of a Ca 2+-sensitive K+ channel (IK channel) that is more …

Migration of transformed renal epithelial cells is regulated by K+ channel modulation of actin cytoskeleton and cell volume

A Schwab, B Schuricht, P Seeger, J Reinhardt… - Pflügers Archiv, 1999 - Springer
Migration of transformed renal epithelial (MDCK-F) cells depends on the polarized activity of
a Ca 2+-sensitive K+ channel (IK channel; Pflügers Arch 432: R87–R93, 1996). This study …

Intracellular Ca2+ distribution in migrating transformed renal epithelial cells

A Schwab, F Finsterwalder, U Kersting, T Danker… - Pflügers Archiv, 1997 - Springer
Abstract Migration of transformed Madin-Darby canine kidney (MDCK-F) cells depends on
the polarized activity of a Ca 2+-sensitive K+ channel. We tested whether a gradient of …

Migrating transformed MDCK cells are able to structurally polarize a voltage-activated K+ channel

J Reinhardt, N Golenhofen, O Pongs… - Proceedings of the …, 1998 - National Acad Sciences
Cell migration of transformed renal epithelial cells (MDCK-F) depends–in addition to
cytoskeletal mechanisms–on the polarized activity of a Ca2+-sensitive K+ channel in the …

Polarized ion transport during migration of transformed Madin-Darby canine kidney cells

A Schwab, K Gabriel, F Finsterwalder, G Folprecht… - Pflügers Archiv, 1995 - Springer
Epithelial cells lose their usual polarization during carcinogenesis. Although most malignant
tumours are of epithelial origin little is known about ion channels in carcinoma cells …

Oscillating activity of a Ca (2+)-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells.

A Schwab, L Wojnowski, K Gabriel… - The Journal of …, 1994 - Am Soc Clin Investig
Migration plays an important role in the formation of tumor metastases. Nonetheless, little is
known about electrophysiological phenomena accompanying or underlying migration …

K+ Channel-Dependent Migration of Fibroblasts and Human Melanoma Cells

A Schwab, J Reinhardt, SW Schneider… - Cellular Physiology and …, 1999 - karger.com
Previously, we showed that migration of transformed renal epithelial cells (MDCK-F cells) is
a K+ channel-dependent process [J Clin Invest 1994; 93: 1631]. In order to determine …

Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopy

H Oberleithner, G Giebisch, J Geibel - Pflügers Archiv, 1993 - Springer
Cell locomotion originates at a specific region of the cell surface, the leading edge of a
migrating cell. Various factors have been proposed to contribute to the propulsion of a cell …

Extracellular detection of K+ release during migration of transformed Madin-Darby canine kidney cells

T Danker, B Gaßner, H Oberleithner, A Schwab - Pflügers Archiv, 1996 - Springer
Madin Darby canine kidney cells transformed by alkaline stress (MDCK-F cells)
constitutively migrate at a rate of about 1 μm· min–1. Migration depends on the intermittent …