Ultrastructural analysis of dendritic spine necks reveals a continuum of spine morphologies

N Ofer, DR Berger, N Kasthuri… - Developmental …, 2021 - Wiley Online Library
Dendritic spines are membranous protrusions that receive essentially all excitatory inputs in
most mammalian neurons. Spines, with a bulbous head connected to the dendrite by a thin …

Ultrastructure of dendritic spines: correlation between synaptic and spine morphologies

JI Arellano, R Benavides-Piccione, J DeFelipe… - Frontiers in …, 2007 - frontiersin.org
Dendritic spines are critical elements of cortical circuits, since they establish most excitatory
synapses. Recent studies have reported correlations between morphological and functional …

Cortical area and species differences in dendritic spine morphology

R Benavides-Piccione, I Ballesteros-Yáñez… - Journal of …, 2002 - Springer
Dendritic spines receive most excitatory inputs in the neocortex and are morphologically
very diverse. Recent evidence has demonstrated linear relationships between the size and …

Structural analysis of human and mouse dendritic spines reveals a morphological continuum and differences across ages and species

N Ofer, R Benavides-Piccione, J DeFelipe, R Yuste - Eneuro, 2022 - eneuro.org
Dendritic spines have diverse morphologies, with a wide range of head and neck sizes, and
these morphologic differences likely generate different functional properties. To explore how …

Density and morphology of dendritic spines in mouse neocortex

I Ballesteros-Yáñez, R Benavides-Piccione, GN Elston… - Neuroscience, 2006 - Elsevier
Dendritic spines of pyramidal cells are the main postsynaptic targets of cortical excitatory
synapses and as such, they are fundamental both in neuronal plasticity and for the …

Systematic regulation of spine sizes and densities in pyramidal neurons

S Konur, D Rabinowitz, VL Fenstermaker… - Journal of …, 2003 - Wiley Online Library
Dendritic spines receive most excitatory inputs in the CNS. Recent evidence has
demonstrated that the spine head volume is linearly correlated with the readily releasable …

Molecular mechanisms of dendritic spine development and remodeling

IM Ethell, EB Pasquale - Progress in neurobiology, 2005 - Elsevier
Dendritic spines are small protrusions that cover the surface of dendrites and bear the
postsynaptic component of excitatory synapses. Having an enlarged head connected to the …

Genesis of dendritic spines: insights from ultrastructural and imaging studies

R Yuste, T Bonhoeffer - Nature Reviews Neuroscience, 2004 - nature.com
Dendritic spines are small protrusions from many types of neuron, which receive most of the
excitatory inputs to the cell. Spines are thought to have important roles in neural information …

Barriers in the brain: resolving dendritic spine morphology and compartmentalization

M Adrian, R Kusters, CJ Wierenga, C Storm… - Frontiers in …, 2014 - frontiersin.org
Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses
in the central nervous system. The head of the spine is connected to the dendritic shaft by a …

The function of dendritic spines: a review of theoretical issues

RG Coss, DH Perkel - Behavioral and neural biology, 1985 - Elsevier
The discovery of dendritic spines in the late nineteenth century has prompted nearly 90
years of speculation about their physiological importance. Early observations that bulbous …