Real‐world data on the efficacy and safety of apremilast in patients with moderate‐to‐severe plaque psoriasis

E Papadavid, N Rompoti… - Journal of the …, 2018 - Wiley Online Library
Background Psoriasis is a chronic inflammatory skin disease, which requires long‐term, safe
and effective treatment. Apremilast, a small‐molecule PDE 4 inhibitor, has been introduced …

Real‐world effectiveness and safety of apremilast in psoriasis at 52 weeks: a retrospective, observational, multicentre study by the Spanish Psoriasis Group

E Del Alcázar, JA Suárez‐Pérez… - Journal of the …, 2020 - Wiley Online Library
Background Little has been published on the real‐world effectiveness and safety of
apremilast in psoriasis. Objectives To evaluate the effectiveness, safety and drug survival of …

Safety and efficacy of apremilast through 104 weeks in patients with moderate to severe psoriasis who continued on apremilast or switched from etanercept treatment …

K Reich, M Gooderham, A Bewley… - Journal of the …, 2018 - Wiley Online Library
Background Apremilast, an oral phosphodiesterase‐4 inhibitor, has demonstrated efficacy in
patients with moderate to severe psoriasis. Objective To evaluate long‐term efficacy and …

Apremilast in psoriasis–a prospective real‐world study

I Vujic, R Herman, M Sanlorenzo… - Journal of the …, 2018 - Wiley Online Library
Background Apremilast is a novel oral phosphodiesterase‐4 inhibitor approved for psoriasis
treatment. Randomized trials have documented its efficacy and safety, but data on real …

The efficacy and safety of apremilast, etanercept and placebo in patients with moderate‐to‐severe plaque psoriasis: 52‐week results from a phase IIIb, randomized …

K Reich, M Gooderham, L Green… - Journal of the …, 2017 - Wiley Online Library
Background Apremilast, an oral, small‐molecule phosphodiesterase 4 inhibitor, has
demonstrated efficacy in patients with moderate‐to‐severe psoriasis. Objective Evaluate …

Quality-of-life outcomes, effectiveness and tolerability of apremilast in patients with plaque psoriasis and routine German dermatology care: results from LAPIS-PSO

K Reich, B Korge, N Magnolo, M Manasterski… - Dermatology and …, 2022 - Springer
Introduction Psoriasis is a systemic inflammatory disease characterised by pruritic skin
lesions that impair quality of life (QOL). Long-Term Documentation of the Utilization of …

Characteristics and outcomes of patients treated with apremilast in the real world: results from the APPRECIATE study

M Augustin, CE Kleyn, C Conrad… - Journal of the …, 2021 - Wiley Online Library
Background APPRECIATE is a multinational, observational, retrospective, cross‐sectional
study in patients treated for psoriasis with apremilast, an oral phosphodiesterase 4 inhibitor …

Efficacy and Safety of Apremilast in Systemic-and Biologic-Naive Patients With Moderate Plaque Psoriasis: 52-Week Results of UNVEIL.

J Bagel, M Lebwohl, JM Jackson, R Chen… - Journal of drugs in …, 2018 - europepmc.org
BACKGROUND: Many patients with moderate plaque psoriasis are undertreated despite
broadening treatment options. In the phase IV UNVEIL study, oral apremilast demonstrated …

Efficacy and safety of apremilast in patients with limited skin involvement, plaque psoriasis in special areas and impaired quality of life: Results from the EMBRACE …

U Mrowietz, J Barker, C Conrad… - Journal of the …, 2023 - Wiley Online Library
Abstract Introduction/Background Manifestations of psoriasis in special areas are difficult to
treat and are associated with a high disease burden and significant quality of life (QoL) …

Efficacy and safety of apremilast in patients with moderate plaque psoriasis with lower BSA: week 16 results from the UNVEIL study

B Strober, J Bagel, M Lebwohl… - Journal of drugs in …, 2017 - pubmed.ncbi.nlm.nih.gov
INTRODUCTION: Many options are available for patients with moderate to severe plaque
psoriasis. Patients with moderate disease, however, are often undertreated and do not …