Wu, Z.(Department of Medical Microbiology, Linkoping University, S-581 85, Linkoping,
Sweden) D. Milton, P. Nybom, A. Sjo and K.-E. Magnusson. Vibrio cholerae hemagglutinin …

The structural gene hap for the extracellular hemagglutinin/protease (HA/protease) of Vibrio
cholerae was cloned and sequenced. The cloned DNA fragment contained a 1,827-bp open …

Vibrio cholerae of serogroup O1 and O139, the etiological agent of the diarrheal disease
cholera, expresses the extracellular Zn-dependent metalloprotease hemagglutinin …

The structural gene, hap, for the secreted hemagglutinin/protease (HA/protease), a putative
virulence factor of Vibrio cholerae, has recently been cloned and sequenced (CC Häse and …

Two forms (34 kDa and 32 kDa) of hemagglutinin/protease produced by Vibrio cholerae non-
O1 were characterized. The hemagglutinin/protease purified by immunoaffinity column …

A soluble hemagglutinin/protease produced by Vibrio cholerae, which has previously been
shown to hydrolyze fibronectin and ovomucin and to cleave lactoferrin and the A subunit of …

Vibrio cholerae of both biotypes produce a soluble Zn2+-dependent metalloprotease:
haemagglutinin/protease (Hap), encoded by hapA. Hap has been shown to have …

A protease produced by a clinical isolate of Vibrio cholerae non-O1 was purified to apparent
homogeneity by ammonium sulfate fractionation and successive column chromatography on …

Culture supernatants of nontoxigenic nonepidemic clinical strains of Vibrio cholerae
belonging to diverse serogroups were found to induce vacuolation of nonconfluent HeLa …

Isoelectric focusing of culture supernatants from Vibrio cholerae El Tor 1621 and high
protease-producing mutant strain 1621 hip revealed the presence of three different types of …