Chewing the fat: How lipidomics is changing our understanding of human health and disease in 2022

C Géhin, SJ Fowler, DK Trivedi - Analytical Science Advances, 2023 - Wiley Online Library
Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

[HTML][HTML] Recent advances towards mass spectrometry-based clinical lipidomics

S Salihovic, S Lamichane, T Hyötyläinen… - Current opinion in …, 2023 - Elsevier
The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

Advances in sample preparation and analytical techniques for lipidomics study of clinical samples

CC Teo, WPK Chong, E Tan, NB Basri, ZJ Low… - TrAC Trends in …, 2015 - Elsevier
Lipids play multiple key roles in biological systems, including acting as secondary energy
reserves, being components of cellular membranes and participating in cell-signaling …

Lipidomics: techniques, applications, and outcomes related to biomedical sciences

K Yang, X Han - Trends in biochemical sciences, 2016 - cell.com
Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

Analytical challenges in human plasma lipidomics: A winding path towards the truth

O Vvedenskaya, Y Wang, JM Ackerman… - TrAC Trends in …, 2019 - Elsevier
Human plasma lipidome has been extensively studied in many pathophysiological contexts
with the hope of identifying biomarkers for early diagnostics and monitoring the progression …

New trends in lipidomics

M Holčapek - Analytical and Bioanalytical Chemistry, 2024 - Springer
Lipidomics encompasses the large-scale identification and quantification of diverse lipids
within biological systems, which play fundamental roles in the metabolism of humans …

A beginner's guide to lipidomics

JV Swinnen, J Dehairs - The Biochemist, 2022 - portlandpress.com
Lipidomics refers to the large-scale analysis of the complete set of lipids–the 'lipidome'–in
any biological system. Methodologically, it heavily relies on mass spectrometry, an analytic …

Lipidomics from sample preparation to data analysis: a primer

T Züllig, M Trötzmüller, HC Köfeler - Analytical and bioanalytical chemistry, 2020 - Springer
Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

Bioanalytical techniques in nontargeted clinical lipidomics

T Hyötyläinen, M Orešič - Bioanalysis, 2016 - Taylor & Francis
Lipidomic analysis aims at comprehensive characterization of molecular lipids in biological
systems. Due to the central role of lipid metabolism in many devastating diseases, lipidomics …

Mass spectrometry based lipidomics: an overview of technological platforms

HC Köfeler, A Fauland, GN Rechberger, M Trötzmüller - Metabolites, 2012 - mdpi.com
One decade after the genomic and the proteomic life science revolution, new 'omics' fields
are emerging. The metabolome encompasses the entity of small molecules—Most often end …