Background Offset analgesia (OA) is characterized by a disproportionately large decrease in
pain perception after a slight decrease in noxious stimulation. In patients with ongoing pain …

Background and aims/objectives Offset analgesia (OA) is a newly discovered pain-inhibiting
mechanism, defined as a disproportionately large decrease in pain perception in response …

Abstract Background Offset Analgesia (OA) can be evoked by a three‐heat‐stimulus train
(T1‐T2‐T3), with T1 (5 s) and T3 (20 s) having the same temperature (eg 48° C) and T2 (5 s) …

Background Offset analgesia (OA) is a pain‐inhibiting mechanism, defined as a
disproportionately large decrease in pain perception in response to a discrete decrease in …

Background Offset analgesia (OA) is a disproportionally large decrease in the pain
perception in response to a small decrease in the stimulation intensity. Traditionally, heat …

Background and aims Offset analgesia (OA) is a pain modulating mechanism described as a
disproportionately large decrease in pain intensity evoked by a minor decrease in stimulus …

Background A noxious stimulus following a more intense stimulus often feels less painful
than continuous noxious stimulation. This effect, known as offset analgesia (OA), may be …

A frequently used paradigm to quantify endogenous pain modulation is offset analgesia,
which is defined as a disproportionate large reduction in pain following a small decrease in …

Objective: Offset analgesia (OA) is a test paradigm increasingly used to estimate
endogenous pain modulation characterized by a disproportionally profound analgesia after …

Objectives: In this study, 2 separate experiments were conducted to investigate both, the
spatial aspects of offset analgesia and the influence of different rates of temperature rise …