Systematic analysis of microRNA biomarkers for diagnosis, prognosis, and therapy in patients with clear cell renal cell carcinoma

G Cheng, M Li, X Ma, F Nan, L Zhang, Z Yan… - Frontiers in …, 2020 - frontiersin.org
The ever-increasing morbidity and mortality of clear cell renal cell carcinoma (ccRCC)
urgently demands updated biomarkers. MicroRNAs (miRNAs) are involved in diverse …

Biomarker identification in clear cell renal cell carcinoma based on miRNA-seq and digital gene expression-seq data

LY Guan, JF Tan, H Li, XF Jin - Gene, 2018 - Elsevier
This study aimed to explore the underlying microRNA (miRNA) targets in clear cell renal cell
carcinoma (ccRCC). The expression profile with accession number GSE24952 was …

Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach

Y Chen, L Teng, W Liu, Y Cao, D Ding, W Wang… - Cancer cell …, 2016 - Springer
Background We aimed to discover the potential microRNA (miRNA) targets and to explore
the underlying molecular mechanisms of clear cell renal cell carcinoma (ccRCC). Methods …

The biological roles and clinical implications of microRNAs in clear cell renal cell carcinoma

Y He, C Chen, Z Shi - Journal of cellular physiology, 2018 - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) accounts for about 3% of tumors in adults as well as
85% of all primary renal carcinoma. And it is the third most predominant urological …

A three-microRNA signature as a diagnostic and prognostic marker in clear cell renal cancer: An In Silico analysis

B Liang, J Zhao, X Wang - PloS one, 2017 - journals.plos.org
Accumulating evidence has demonstrated that some specific miRNAs were aberrantly
expressed in renal clear cell carcinoma and participated in many biological processes. The …

Identification of biomarkers and construction of a microRNA‑mRNA regulatory network for clear cell renal cell carcinoma using integrated bioinformatics analysis

M Han, H Yan, K Yang, B Fan, P Liu, H Yang - Plos one, 2021 - journals.plos.org
With the recent research development, the importance of microRNAs (miRNAs) in renal
clear cell carcinoma (CCRCC) has become widely known. The purpose of this study is to …

Identification of potential biomarkers for clear cell renal cell carcinoma based on microRNA-mRNA pathway relationships

JF Hao, KM Ren, JX Bai, SN Wang… - Journal of cancer …, 2014 - journals.lww.com
Background: MicroRNAs (miRNAs) play important roles in tumor genesis. miRNA
dysregulation has been widely studied and demonstrated in clear cell renal cell carcinoma …

A tumor-specific microRNA signature predicts survival in clear cell renal cell carcinoma

YZ Ge, R Wu, H Xin, M Zhu, TZ Lu, H Liu, Z Xu… - Journal of cancer …, 2015 - Springer
Purpose Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney
cancers in adults, and microRNAs (miRNAs) differentially expressed in ccRCC tumors have …

Profiling of Serum miRNAs Constructs a Diagnostic 3-miRNA Panel for Clear-Cell Renal Cell Carcinoma

X Li, Z Wen, R Li, C Lu, W Chen, X Chen… - Clinical Genitourinary …, 2024 - Elsevier
Background: Renal cell carcinoma (RCC) carries significant morbidity and mortality globally
with an increasing incidence per year predominantly represented by clear-cell renal cell …

[HTML][HTML] Identification of dysregulated serum miR-508-3p and miR-885-5p as potential diagnostic biomarkers of clear cell renal carcinoma

S Liu, X Deng, J Zhang - Molecular medicine reports, 2019 - spandidos-publications.com
Clear cell renal cell carcinoma (ccRCC), the most common subtype, accounts for
approximately 80% of all RCC cases. ccRCC patients typically present with an advanced …