Abstract In Sprague-Dawley rats at the ages of 5 weeks (young) and 9 months (adult), the
activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in age-matched …

Activities of the hepatic cholesterol synthetic system including initial steps of the pathway
and cholesterol 7α-hydroxylase were all lower in adult (8 to 9-month-old) rats than in young …

Various aspects of lipid metabolism were compared in Fisher 344 (F) and Sprague‐Dawley
(SD) rats aged 2, 6, 12, 18 and 24 months. The analyses included free and total cholesterol …

Lipid metabolism of male Fisher 344 rats aged 2–24 months was studied. Serum and liver
cholesterol levels did not display the age-related gradual increase seen in other rat strains …

Abstract Male Sprague-Dawley rats, 3 weeks of age, received one of the four following
dietary manipulations until 9 months of age: group AD, fed ad libitum; group R, restricted to …

The effects of aging on the hepatic metabolism of cholesterol were studied in 1-, 6-and 24-
month-old male Sprague-Dawley rats. Microsomal 3-hydroxy-3-methylglutaryl coenzyme A …

For three weeks, male Sprague‐Dawley rats at either four weeks (young) or eight months
(adult) of age were pairfed one of the purified diets free of or containing either 0.2% of …

There was great individual variation in the elevations of serum cholesterol concentrations in
a Wistar strain of rats by the ingestion of a large amount of cholesterol, although their …

When a hypercholemic diet was fed to rats of different ages for 4 days, older rats (adult)
showed higher serum cholesterol levels than younger rats (growing), but both groups of rats …

We examined the cholesterol metabolism of homozygous Watanabe heritable
hyperlipidemic (WHHL) rabbits, an animal model deficient in low-density lipoprotein (LDL) …