[HTML][HTML] Tumour-and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review

L Khoja, D Day, TWW Chen, LL Siu, AR Hansen - Annals of Oncology, 2017 - Elsevier
Background Immune checkpoint inhibitor (ICI) monoclonal antibodies (mAbs) targeting
cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed cell death protein 1 (PD-1) or its …

The biomarkers related to immune related adverse events caused by immune checkpoint inhibitors

XH Jia, LY Geng, PP Jiang, H Xu, KJ Nan… - Journal of Experimental …, 2020 - Springer
The enthusiasm for immune checkpoint inhibitors (ICIs), an efficient tumor treatment model
different from traditional treatment, is based on their unprecedented antitumor effect, but the …

[HTML][HTML] Immune-related adverse events as potential surrogates of immune checkpoint inhibitors' efficacy: a systematic review and meta-analysis of randomized …

V Amoroso, F Gallo, A Alberti, D Paloschi, WF Bravo… - ESMO open, 2023 - Elsevier
Background Immune-related adverse events (irAEs) are frequently reported during immune
checkpoint inhibitor (ICI) therapy and are associated with long-term outcomes. It is unknown …

Immune-related adverse events and anti-tumor efficacy of immune checkpoint inhibitors

S Das, DB Johnson - Journal for immunotherapy of cancer, 2019 - Springer
Although immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for
patients with many advanced malignancies, only 15–60% of patients respond, leaving a …

Cancer and treatment specific incidence rates of immune-related adverse events induced by immune checkpoint inhibitors: a systematic review

B Jayathilaka, F Mian, F Franchini, G Au-Yeung… - British Journal of …, 2024 - nature.com
Background Immune-related adverse events (irAE) induced by immune checkpoint inhibitors
(ICI) are a treatment-limiting barrier. There are few large-scale studies that estimate irAE …

Comprehensive meta-analysis of key immune-related adverse events from CTLA-4 and PD-1/PD-L1 inhibitors in cancer patients

G De Velasco, Y Je, D Bossé, MM Awad, PA Ott… - Cancer immunology …, 2017 - AACR
Immune-related adverse events (irAE) have been described with immune checkpoint
inhibitors (ICI), but the incidence and relative risk (RR) of irAEs associated with these drugs …

Immune-related adverse events (irAE) in cancer immune checkpoint inhibitors (ICI) and survival outcomes correlation: to rechallenge or not?

HJ Albandar, J Fuqua, JM Albandar, S Safi, SA Merrill… - Cancers, 2021 - mdpi.com
Simple Summary This study examined the real-world experience and occurrence of immune-
related adverse events (irAEs) under cancer checkpoint immunotherapy, and the …

[HTML][HTML] Immune-related adverse events associated with immune checkpoint inhibitors: a call to action for collecting and sharing clinical trial and real-world data

KL Reynolds, S Arora, RK Elayavilli… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer, improving
outcomes in patients with advanced malignancies. The use of ICIs in clinical practice, and …

Not all immune-checkpoint inhibitors are created equal: meta-analysis and systematic review of immune-related adverse events in cancer trials

B El Osta, F Hu, R Sadek, R Chintalapally… - Critical reviews in …, 2017 - Elsevier
Background Targeting immune checkpoints is a novel approach in cancer therapy. This
strategy may trigger immune related adverse events (irAE). We hypothesize that the …

Are immune-related adverse events associated with the efficacy of immune checkpoint inhibitors in patients with cancer? A systematic review and meta-analysis

X Zhou, Z Yao, H Yang, N Liang, X Zhang, F Zhang - BMC medicine, 2020 - Springer
Background A number of studies have reported an association between the occurrence of
immune-related adverse events (irAEs) and clinical efficacy in patients undergoing treatment …