Cholesterol metabolism is modulated by quercetin in rats

L Zhao, J Wu, Y Wang, J Yang, J Wei… - Journal of agricultural …, 2011 - ACS Publications
Quercetin has attracted much attention recently because of its antioxidant capacity and
potential in the prevention of chronic degenerative diseases. However, its actions and the …

Quercetin regulates hepatic cholesterol metabolism by promoting cholesterol-to-bile acid conversion and cholesterol efflux in rats

M Zhang, Z Xie, W Gao, L Pu, J Wei, C Guo - Nutrition research, 2016 - Elsevier
Quercetin, a common member of the flavonoid family, is widely present in plant kingdom.
Despite that quercetin is implicated in regulating cholesterol metabolism, the molecular …

Protective effect of dietary flavonoid quercetin against lipemic-oxidative hepatic injury in hypercholesterolemic rats

AD Mariee, GM Abd-Allah… - Pharmaceutical …, 2012 - Taylor & Francis
Context: Quercetin, a dietary-derived flavonoid, is ubiquitous in fruits and vegetables and
plays important roles in human health by virtue of its antioxidant activity. Objective: This …

Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice

SM Jeong, MJ Kang, HN Choi… - Nutrition research and …, 2012 - synapse.koreamed.org
This study investigated the hypoglycemic, hypolipidemic, and antioxidant effects of dietary
quercetin in an animal model of type 2 diabetes mellitus. Four-week-old C57BL/KsJ-db/db …

Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice

EF Hoek-Van Den Hil, J Keijer, A Bunschoten… - PloS one, 2013 - journals.plos.org
Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In
order to examine the effects of quercetin on lipid metabolism, mice received a mild-high-fat …

The therapeutic effects and mechanisms of quercetin on metabolic diseases: pharmacological data and clinical evidence

H Yi, H Peng, X Wu, X Xu, T Kuang… - Oxidative medicine …, 2021 - Wiley Online Library
Metabolic diseases have become major public health issues worldwide. Searching for
effective drugs for treating metabolic diseases from natural compounds has attracted …

Dietary quercetin supplementation increases serum antioxidant capacity and alters hepatic gene expression profile in rats

L Zhao, J Wu, J Yang, J Wei… - … Biology and Medicine, 2011 - journals.sagepub.com
The aim of this study was to determine the effect of quercetin on hepatic gene expression
profile in rats. Twenty male Wistar rats were divided into the control group and the quercetin …

Chronic high intake of quercetin reduces oxidative stress and induces expression of the antioxidant enzymes in the liver and visceral adipose tissues in mice

M Kobori, Y Takahashi, Y Akimoto, M Sakurai… - Journal of Functional …, 2015 - Elsevier
To obtain knowledge regarding the safe intake of quercetin-rich functional foods, we
examined the effect of chronic and high intake of quercetin. We fed mice a standard diet …

Quercetin Regulates Lipid Metabolism and Fat Accumulation by Regulating Inflammatory Responses and Glycometabolism Pathways: A Review

Y Wang, Z Li, J He, Y Zhao - Nutrients, 2024 - mdpi.com
Fat synthesis and lipolysis are natural processes in growth and have a close association
with health. Fat provides energy, maintains physiological function, and so on, and thus plays …

Metabolic profiling of quercetin in rats using ultra‐performance liquid chromatography/quadrupole‐time‐of‐flight mass spectrometry

M Wu, X Wu, D Zhang, F Qiu, L Ding… - Biomedical …, 2017 - Wiley Online Library
Quercetin, a kind of major flavonoid found in many traditional chinese medicines, is an
effective substance for treatments such as lowering blood lipids. However, the studies on …