Asthenoteratozoospermia is the primary cause of infertility in humans. However, the genetic
etiology remains largely unknown for those suffering from severe asthenoteratozoospermia …

Infertility affects around 8%–12% of reproductive-aged couples and is a major health
concern. Both genetic and environmental factors influence male infertility. SEPTIN12 is a …

Septins are members of the GTPase superfamily, which has been implicated in diverse
cellular functions including cytokinesis and morphogenesis. Septin 12 (SEPT12) is a testis …

The main objective of this study was to evaluate the potential genetic effects of SEPT14 on
male infertility through sequencing the SEPT14 coding region. To address this research gap …

It is estimated that 10–15% of couples are infertile and male factors account for about half of
these cases. With the advent of intracytoplasmic sperm injection (ICSI), many infertile men …

SEPT12 is a testis‐specific gene involved in the terminal differentiation of male germ cells.
SEPT12 protein is required for sperm head‐tail formation and acts as a fundamental …

Purpose To find a relationship between absence of annulus and asthenozoospermia in
Iranian men. Methods In the present study, semen samples from 100 asthenozoospermic …

Purpose: Septins are the major constituents of the annulus, a submembranous ring that
separates the middle and principal pieces of spermatozoa. We previously reported its …

Male infertility is a complex multifactorial disease affecting approximately 10% of couples
who want to have children. Some cases of infertility can be explained by genetic factors …

The annulus is a septin-based ring structure located at the junction of the midpiece (MP) and
the principal piece (PP) of spermatozoa flagellum. In the mouse, deletion of Septin 4, a …