Rate of cognitive decline in preclinical Alzheimer's disease: the role of comorbidity

L Bäckman, S Jones, BJ Small… - The Journals of …, 2003 - academic.oup.com
We investigated the influence of individual-difference variables implicated as risk factors for
Alzheimer's disease (AD) or known to be related to cognitive performance in normal aging …

Cognitive decline in Alzheimer's disease: a longitudinal investigation of risk factors for accelerated decline

L Teri, SM McCurry, SD Edland… - The Journals of …, 1995 - academic.oup.com
Abstract Background.—Although Alzheimer's disease (AD) is a progressive degenerative
condition, there is great intra-and inter-individual variability in rates of cognitive decline …

Cognitive deterioration in Alzheimer's disease behavioral and health factors

L Teri, JP Hughes, EB Larson - Journal of Gerontology, 1990 - academic.oup.com
Alzheimer's disease is characterized by progressive cognitive decline. However, little is
known about the “typical” rate of decline, the degree of individual heterogeneity evident in …

Cognitive decline from estimated premorbid status predicts neurodegeneration in Alzheimer's disease.

O Almkvist, IM Tallberg - Neuropsychology, 2009 - psycnet.apa.org
This study investigated the relationship between premorbid and current cognitive function
with respect to the clinical features of patients with various types of neurodegeneration in the …

Age at onset of Alzheimer's disease: relation to pattern of cognitive dysfunction and rate of decline

D Jacobs, M Sano, K Marder, K Bell, F Bylsma… - Neurology, 1994 - AAN Enterprises
We examined the pattern of cognitive impairment and rate of cognitive and functional
decline as a function of age at symptom onset in 127 patients with probable Alzheimer's …

The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study

H Amieva, H Jacqmin-Gadda, JM Orgogozo… - Brain, 2005 - academic.oup.com
Better knowledge of the preclinical phase of Alzheimer's disease would be an important
advance to allow earlier treatment of this ominous disease. This prodromal period was …

A cognitive turning point in development of clinical Alzheimer's disease dementia and mild cognitive impairment: A biracial population study

KB Rajan, RS Wilson, LL Barnes… - … Series A: Biomedical …, 2017 - academic.oup.com
Background: Cognitive changes during the preclinical phase of Alzheimer's disease (AD)
dementia have been characterized among European Americans (EAs), but studies of …

Aβ and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease

YY Lim, P Maruff, RH Pietrzak, KA Ellis, D Darby… - Alzheimer's & …, 2014 - Elsevier
Background High β-amyloid (Aβ) is associated with faster memory decline in healthy
individuals and adults with mild cognitive impairment (MCI). However, longer prospective …

Cognitive differences between early-and late-onset Alzheimer's disease

EA Licht, AM McMurtray, RE Saul… - American Journal of …, 2007 - journals.sagepub.com
Although neuropathologic studies showed that early-onset Alzheimer's disease (EAD) and
“senile dementia” were indistinguishable, clinical studies suggested that EAD and late-onset …

From subjective cognitive decline to Alzheimer's disease: The predictive role of neuropsychological assessment, personality traits, and cognitive reserve. A 7-year …

V Bessi, S Mazzeo, S Padiglioni… - Journal of …, 2018 - content.iospress.com
The aim of this study was to evaluate the accuracy of neuropsychological assessment in
predicting conversion from subjective cognitive decline (SCD) and mild cognitive impairment …