Cloned mammals with normal fertility have been produced by nuclear transfer. Thus, oocyte
cytoplasm has the ability to convert differentiated somatic cell nuclei into a state that …

Nuclear transfer has been regarded as the only reliable tool for studying nuclear
reprogramming of mammalian somatic cells by oocytes. However, nuclear transfer is not …

Nuclear transfer (NT) is used to elucidate fundamental biological issues such as reversibility
of cell differentiation and interactions between the cytoplasm and nucleus. To obtain an …

Relatively little is known with respect to the oocyte proteins that are involved in nuclear
reprogramming of somatic cells in mammals. The aim of the present study was to use a cell …

The transfer of nuclei from one cell to another provides a powerful tool for studying the
interactions between the cytoplasm of one cell and the nucleus of another. This study was …

The reason for the poor development of cloned embryos is not yet clear. Several reports
have suggested that some nuclear remodeling/reprogramming factors (RRFs) are removed …

The transplantation of a somatic cell nucleus to an enucleated egg results in a major
reprogramming of gene expression and switch in cell fate. We review the efficiency of …

Fertile offspring have been produced by nuclear transfer from adult somatic cells in several
mammalian species (Wilmut et al., 1997; Kato et al., 1998; Wakayama et al., 1998; …

Effective activation of a recipient oocyte and its compatibility with the nuclear donor are
critical to the successful nuclear reprogramming during nuclear transfer. We designed a …

Increased possibility of universality of ooplasmic reprogramming factors resulted in a
parallel increased interest to use interspecies somatic cell nuclear transfer (iSCNT) to …