Disturbed homocysteine metabolism may contribute to amyloidogenesis by modulating the
amyloid precursor protein (APP) production and processing. The objective of this study was …

Recent epidemiological and clinical data suggest that elevated serum homocysteine levels
may increase the risk of developing Alzheimer's disease (AD), but the underlying …

Disturbed homocysteine metabolism is a risk factor for Alzheimer's disease (AD) and may
contribute to the disease pathophysiology by increasing both amyloid-β (Aβ) production and …

Alzheimer's disease (AD) patients tend to have increased plasma levels of homocysteine.
However, it is unclear whether abnormality in homocysteine levels is a primary cause of …

Background Elevated plasma homocysteine and amyloid β (Aβ) have been associated with
Alzheimer's disease (AD). We investigated the cross-sectional association between these …

Observational studies have consistently reported elevated plasma homocysteine as a risk
factor for Alzheimer's disease (AD). However, results from clinical trials of homocysteine …

Purpose Homocysteine has been associated with cognitive impairment and various
psychiatric symptoms. This study was designed to clarify whether a relationship exists …

Background: Identifying modifiable risk factors for cognitive decline can reduce burden of
dementia. Objective: We examined whether homocysteine was associated with memory …

OBJECTIVE: Elevated homocysteine is associated with a variety of diseases, including
Alzheimer's disease (AD) and depressive disorder. This study was designed to detect an …

Elevated plasma homocysteine (tHcy) concentrations have been associated with an
increased risk of developing dementia and Alzheimer's disease (AD). It is not clear …