Targeting of the pro-oxidant-antioxidant balance in vitro and in vivo by 4-thiazolidinone-based chemotherapeutics with anticancer potential
L Kobylinska, O Klyuchivska, R Lesyk… - The Ukrainian …, 2019 - irbis-nbuv.gov.ua
Accepted: 20 March 2019 oxidative stress is one of the main mechanisms by which
anticancer chemotherapeutics damage normal tissues and organs. at the same time, it is an …
anticancer chemotherapeutics damage normal tissues and organs. at the same time, it is an …
[PDF][PDF] Indicators of oxidative and nitrosative stress and activity of enzymes of nitric oxide metabolism in rats treated with 4-thiazolidinone derivatives possessing …
Principal ways of generation and function of free oxygen and nitrogen radical metabolites,
as well as the ways of their bio-neutralization in rats treated with potential anticancer drugs …
as well as the ways of their bio-neutralization in rats treated with potential anticancer drugs …
[PDF][PDF] Putative anticancer potential of novel 4-thiazolidinone derivatives: cytotoxicity toward rat C6 glioma in vitro and correlation of general toxicity with the balance of …
LI Коbylinska, NM Boiko, RR Panchuk… - Croatian medical …, 2016 - hrcak.srce.hr
Methods Glioma cells were treated with ID 3882, ID 3288, ID 3833, and doxorubicin, and
their cytotoxicity was studied using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5 …
their cytotoxicity was studied using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5 …
[PDF][PDF] Prooxidant and antioxidant processes in the liver homogenate of healthy and tumor-bearing mice under the action of thiazole derivatives
YR Shalai, MV Popovych… - The Ukrainian …, 2021 - ukrbiochemjournal.org
Thiazole derivatives were shown to have toxic effects in vitro on cancer cells of different
origin and can be considered as potentially antineoplastic, but their effect on the normal …
origin and can be considered as potentially antineoplastic, but their effect on the normal …
Comparative study of the cytotoxic properties of isatin-containing derivatives of 4-thiazolidinone with different structure toward human tumor cells in vitro
VV Chumak, RR Panchuk, NO Manko… - Біологічні студії …, 2014 - publications.lnu.edu.ua
Compounds on the basis of 4-thiazolidinone and its isatin-containing derivatives are
characterized by a broad spectrum of biological activities and are potential antineoplastic …
characterized by a broad spectrum of biological activities and are potential antineoplastic …
[PDF][PDF] Biochemical indicators of nephrotoxicity in blood serum of rats treated with novel 4-thiazolidinone derivatives or their complexes with polyethylene glycol …
1Danylo Halytsky Lviv National Medical University, Ukraine; e-mail: stoika@ cellbiol. lviv. ua;
2Lviv Polytechnic National University, Ukraine; 3іnstitute of cell biology, national academy of …
2Lviv Polytechnic National University, Ukraine; 3іnstitute of cell biology, national academy of …
Modifications of the erythrocytic antioxidant system in the administration of new coordinative compounds
Background. Currently, there is a growing interest in new local coordination compounds
(CC), which demonstrated antitumor properties, but their influence on the erythrocyte …
(CC), which demonstrated antitumor properties, but their influence on the erythrocyte …
Effect of novel 2-amino-5-benzylthiazole derivative on cellular ultrastructure and activity of antioxidant system in murine lymphoma cells
YR Shalai, MV Popovych… - Біологічні студії …, 2019 - publications.lnu.edu.ua
The influence of newly synthesized thiazole derivative N-(5-benzyl-1, 3-thiazol-2-yl)-3, 5-
dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and antioxidant system …
dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and antioxidant system …
Study of rat blood serum biochemical indicators of cardiotoxic action of novel antitumor 4-thiazolidinone derivatives and doxorubicin in complexes with polyethylene …
LI Kobylyns' ka, H DIa, AO Riabtseva, M NIe… - Ukrainian …, 2014 - europepmc.org
The aim of this study was to measure the activity of enzymes which reflect cardiotoxic action
in rats of novel synthetic 4-thiazolidone derivatives--3882, 3288 and 3833 that demonstrated …
in rats of novel synthetic 4-thiazolidone derivatives--3882, 3288 and 3833 that demonstrated …
Biochemical indicators of hepatotoxicity in blood serum of rats under the effect of novel 4-thiazolidinone derivatives and doxorubicin and their complexes with …
LI Kobylinska, DY Havrylyuk… - The Ukrainian …, 2015 - irbis-nbuv.gov.ua
2Lviv Polytechnic national university, ukraine; 3іnstitute of cell biology, national academy of
sciences of ukraine, Lviv the aim of this study was to compare the effect of new synthetic 4 …
sciences of ukraine, Lviv the aim of this study was to compare the effect of new synthetic 4 …