Sodium current (INa) block by amiodarone (AMI) was investigated in isolated single Purkinje
and ventricular myocardial cells using the single suction-pipette voltage-clamp technique …

Acute effects of amiodarone on cardiac sodium channels were investigated in ventricular
myocytes isolated from guinea-pig hearts, and compared with those of lignocaine. 2 …

Amiodarone has become an important agent for the management of life-threatening cardiac
arrhythmias, especially those occurring after myocardial infarction. Its mode of action has not …

Ca current (l) block by amiodarone and the underlying mechanisms thereof were
investigated in guinea pig single ventricular myocytes using the single suction pipette whole …

The acute and chronic effects of amiodarone were studied on the transmembrane ionic
currents in rabbit single ventricular myocytes at 35 degrees C by applying the whole-cell …

Introduction: Amiodarone (AM) is a highly effective antiarrhythmic agent used in the
management of both atrial and ventricular arrhythmias. Its noniodinated analogue …

The electrophysiological effects of amiodarone were studied in guinea pig papillary muscle
by means of the single sucrose gap voltage clamp technique. The first time derivative of the …

In guinea pig cardiac myocytes quinidine (20 microM) caused less than 10% tonic block
reduction of the sodium current at-120 mV, but a fast pulse train reduced it more than 90 …

The state-dependent sodium channel block by mexiletine, tocainide, lidocaine, OPC-88117,
aprindine, quinidine, disopyramide and AN-132 was investigated in single ventricular …

Effects of ethmozine (moricizine) on the rapid inward sodium current (I Na) were studied in
freshly isolated single cells of rat ventricular myocardium. I Na was measured by means of a …