Molecular mechanisms of dendritic spine development and remodeling

IM Ethell, EB Pasquale - Progress in neurobiology, 2005 - Elsevier
Dendritic spines are small protrusions that cover the surface of dendrites and bear the
postsynaptic component of excitatory synapses. Having an enlarged head connected to the …

Structure, development, and plasticity of dendritic spines

KM Harris - Current opinion in neurobiology, 1999 - Elsevier
Dendritic spines are distinguished by their shapes, subcellular composition, and synaptic
receptor subtypes. Recent studies show that actin-dependent movements take place in …

Growth of dendritic spines: a continuing story

A Matus - Current opinion in neurobiology, 2005 - Elsevier
Dendritic spines, which are present at the vast majority of excitatory synapses in the central
nervous system, have a specialized cytoskeleton of dynamic actin filaments that makes them …

Regulation of the actin cytoskeleton in dendritic spines

P Penzes, I Rafalovich - Synaptic Plasticity: Dynamics, Development and …, 2012 - Springer
Spine morphogenesis is largely dependent on the remodeling of the actin cytoskeleton.
Actin dynamics within spines is regulated by a complex network of signaling molecules …

Development and regulation of dendritic spine synapses

B Calabrese, MS Wilson, S Halpain - Physiology, 2006 - journals.physiology.org
Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic
component of most excitatory synapses in the brain. They play critical roles in synaptic …

Dendritic spine morphogenesis and plasticity

J Lippman, A Dunaevsky - Journal of neurobiology, 2005 - Wiley Online Library
Dendritic spines are small protrusions off the dendrite that receive excitatory synaptic input.
Spines vary in size, likely correlating with the strength of the synapses they form. In the …

Development and molecular organization of dendritic spines and their synapses

W Zhang, DL Benson - Hippocampus, 2000 - Wiley Online Library
Nearly all excitatory input in the hippocampus impinges on dendritic spines which serve as
multifunctional compartments that can, at the very least, selectively isolate and amplify …

Dentritic spines: structure, dynamics and regulation

H Hering, M Sheng - Nature Reviews Neuroscience, 2001 - nature.com
Dendritic spines are tiny protrusions that receive excitatory synaptic input and
compartmentalize postsynaptic responses. Heterogeneous in size and shape, and …

Actin cytoskeleton in dendritic spine development and plasticity

W Lei, OF Omotade, KR Myers, JQ Zheng - Current opinion in neurobiology, 2016 - Elsevier
Highlights•Dendritic spines depend on the actin cytoskeleton and its remodeling for their
structure and plasticity.•Actin nucleation factors enable the formation and growth of distinct F …

Actin in dendritic spines: connecting dynamics to function

P Hotulainen, CC Hoogenraad - Journal of Cell Biology, 2010 - rupress.org
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …